Practice
#reconstitution
Swirl, do not shake. mg/ml, unit conversion, recon volume choice.
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The maths channel. Choosing a reconstitution volume so your doses land on round unit marks, bacteriostatic versus sterile water, why benzyl alcohol matters for a multi-use vial, needle dead space, the vacuum in a lyophilised vial, and the single most repeated correction in the archive: one insulin unit is 0.01ml.
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ONE UNIT IS 0.01ml ON A U-100 SYRINGE. 100 units is 1ml. If you remember nothing else from this channel, remember this.
Pick your recon volume so your dose lands on a round number of units. 10mg in 2ml gives 5mg/ml, so 0.5mg is 10 units. Do that instead of fighting a 1.37ml answer for the next eight weeks.
Bacteriostatic water for anything you will enter more than once. Sterile water has no preservative.
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2026-06-30check your maths34 msgs · 6 people2026-06-29i was wrong about this last year: it is fine to draw cold, it just stings more going in, thats one data point65 msgs · 14 people2026-06-27what do you do with the last 5 units when you cant draw them cleanly17 msgs · 5 people2026-06-26swirl dont shake19 msgs · 4 people2026-06-25round numbers52 msgs · 11 people2026-06-24swirl it. do not shake it. the foam is denatured protein and you are not getting it back17 msgs · 5 people2026-06-21i use bac water even for a single-use vial because it stings less, which is not the reason it exists66 msgs · 15 people2026-06-20how long after reconstituting before its actually dissolved27 msgs · 6 people2026-06-18slightly off topic but dead space in a standard insulin syringe hub is small but it is not nothing over a month50 msgs · 11 people2026-06-16nope, redo it46 msgs · 7 people2026-06-14weighing the vial before you reconstitute is the only way to catch an underfill, happy to be corrected16 msgs · 3 people2026-06-13swirl dont shake61 msgs · 12 people2026-06-09im getting bubbles in the barrel every single time, what am i doing wrong36 msgs · 8 people2026-06-08anyone else find the 2mg vials harder to get fully dissolved than the small ones19 msgs · 4 people2026-06-06dead space in a standard insulin syringe hub is small but it is not nothing over a month17 msgs · 6 people2026-06-05if you draw up with a bigger pin and inject with a fresh one you lose a bit more to dead space44 msgs · 7 people2026-06-01weigh it first21 msgs · 4 people2026-05-29if the powder is on the stopper, tap it down before you add anything. it will still dissolve either way50 msgs · 12 people2026-05-28swirl it. do not shake it. the foam is denatured protein and you are not getting it back57 msgs · 14 people2026-05-27clear or bin it58 msgs · 12 people2026-05-26gross powder mass is not net peptide. water and counterion are in that number swirl it. do not shake it. the foam is…58 msgs · 14 people2026-05-2530mg in 3ml is 10mg/ml, so 5mg is 50 units. half the barrel, feels like a lot but its right58 msgs · 11 people2026-05-2420mg in 2ml is 10mg/ml. 1mg is 10 units, 2mg is 20 units, easy23 msgs · 5 people2026-05-23weigh it first56 msgs · 12 people2026-05-22swirl it. do not shake it. the foam is denatured protein and you are not getting it back14 msgs · 4 people2026-05-21anyone else find the 30mg vials harder to get fully dissolved than the small ones28 msgs · 5 people2026-05-19foam is bad24 msgs · 5 people2026-05-18gross powder mass is not net peptide. water and counterion are in that number, anyway62 msgs · 12 people2026-05-16if the maths gives you 13.7 units, change the volume. do not try to hit 13.750 msgs · 8 people2026-05-12follow up i was wrong about this last year: it is fine to draw cold, it just stings more going in26 msgs · 8 people
Threads spun off from this channel
does it matter if i inject the bac water2026-05-08 · 16 msgsi write the mg/ml on the vial with a2026-04-25 · 10 msgsif you cannot read the mark confidently, your volume2026-04-12 · 8 msgsif you cannot read the mark confidently, your volume2026-04-11 · 6 msgsone unit is 0.01ml. 100 units is 1ml. everything2026-02-20 · 13 msgsa slightly collapsed cake is cosmetic. a puddle in2026-02-14 · 11 msgspicking a recon volume so your doses land on whole units2026-01-23 · 5 msgscan i add more bac water later to a2026-01-16 · 11 msgsfollow up 20mg in 2ml is 10mg/ml. 1mg is2025-12-11 · 8 msgsthe last few units are a real loss. i2025-11-14 · 13 msgsa 3ml syringe for the diluent and a u1002025-11-08 · 14 msgsbac water or sterile water for something im going2025-09-25 · 10 msgsPeptideMeter not the other one2025-08-27 · 13 msgsaim the diluent at the glass wall, not at2025-07-29 · 9 msgsi was wrong about this last year: it is2025-07-27 · 13 msgslabel the date too. you will not remember which2025-07-22 · 9 msgsgive it 2 minutes at room temperature before you2025-07-20 · 15 msgswhile im here you can absolutely just always use2025-06-02 · 11 msgstemperature of the diluent does not matter. how fast2025-04-17 · 15 msgstook me a year to stop over-diluting. the measurement2025-03-31 · 15 msgsanyone got a photo of what a properly dissolved2025-03-06 · 17 msgswhat do you do with the last 50 units2025-03-03 · 5 msgsdead space in a standard insulin syringe hub is2025-01-12 · 9 msgswhy does everyone say 2ml specifically and not 1ml2025-01-09 · 14 msgs