vialroom

#reconstitution 2026-01-16

Friday48 messages10 participantstimes are UTC
Highlights from this day
  • no_appetite_nia — if the powder is on the stopper, tap it down before you add anything. it will still dissolve either way i use bac water even for a single-use vial because it stings… 12:24
  • no_appetite_nia — is a slightly cloudy solution ever ok or is that always a bin it 12:32
  • abdo_two_inch — i write the mg/ml on the vial with a sharpie the moment i reconstitute it 14:02
  • abdo_two_inch — can i add more bac water later to a vial ive already reconstituted 14:08
CH

benzyl alcohol is what makes it bacteriostatic. it is about 0.9% typically

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CH

coming back after 13 months, has the pinned recon volume advice changed

📉9

20mg in 2ml is 10mg/ml. 1mg is 10 units, 2mg is 20 units, easy

i have never once regretted using a rounder number and a slightly bigger volume

MO

5mg in 2ml gives 2.5mg/ml, 0.25mg is 10 units. good for a starting dose

🧊24

anyone got a photo of what a properly dissolved vial looks like

12😂3💀1

sorry to jump in if you draw up with a bigger pin and inject with a fresh one you lose a bit more to dead space

aim the diluent at the glass wall, not at the powder. it goes in gentler

weigh it first

too dilute imo

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NA

if the powder is on the stopper, tap it down before you add anything. it will still dissolve either way
i use bac water even for a single-use vial because it stings less, which is not the reason it exists

🤝6👀7📉2

does temperature of the bac water matter at all

dead space

10mg in 2ml is 5mg/ml. so 0.5mg is 0.1ml which is 10 units on a u100, i have it written down somewhere
do not add more bac water to an already reconstituted vial, you have lost track of the concentration

it foamed. is it ruined

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not sterile water

is a slightly cloudy solution ever ok or is that always a bin it

💀18

do not add more bac water to an already reconstituted vial, you have lost track of the concentration

A1

you can absolutely just always use 2ml, and honestly most of us should

TE

give it 9 minutes at room temperature before you decide it has not dissolved

NA

lyophilised powder is far more robust than people think. it is the solution that is fragile

foam is bad

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check your maths

the jewellery scale is a good habit but calibrate it, they drift badly

*PeptideMeter not the other one

label the date too. you will not remember which vial is which by week 21, thats just me

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DD

thats 5mg/ml

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is it worth buying a 3ml syringe for the diluent or is the insulin one fine

AT

i write the mg/ml on the vial with a sharpie the moment i reconstitute it

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i keep a spare vial of bac water in the fridge purely so i never rush the maths

follow up sanity check my maths before i pin myself with something stupid

[edited]

does it matter if i inject the bac water straight at the powder

LL

read it at eye level

U-100 syringe: 1 unit = 0.01 ml
  10u = 0.10 ml
  25u = 0.25 ml
  50u = 0.50 ml
 100u = 1.00 ml
mg drawn = ml drawn x mg/ml
LL

my rule is one concentration for everything so i never have to think about it at 7am, thats just me

LL

one unit is 0.01ml. 100 units is 1ml. everything else in this channel follows from that

how long after reconstituting before its actually dissolved

NA

i was wrong about this last year: it is fine to draw cold, it just stings more going in

AA

sorry to jump in a 3ml syringe for the diluent and a u100 for the dose is the setup most people here end up with, i could be wrong