vialroom

#reconstitution 2026-05-16

Saturday50 messages8 participantstimes are UTC
Highlights from this day
  • seoul_swirl — the meniscus thing is real. read it at eye level or you are guessing by a unit either way 11:11
  • truncation_tru — i keep a spare vial of bac water in the fridge purely so i never rush the maths 11:35
  • deadspace — how much do i lose to dead space with a 29G pin 14:42
  • lisbon_lot — i swirl for about thirty seconds and then leave it. never had one fail to dissolve 14:47
  • VialBot — Archive lookup: deadspace first appears in this channel on 2025-12-01. 16:55
CO

if the maths gives you 13.7 units, change the volume. do not try to hit 13.7

do i swirl for a specific length of time or just until its clear

is a slightly cloudy solution ever ok or is that always a bin it

SS

right so my 10mg vial weighed 11.4g on the jewellery scale, is that wrong

SS

30mg in 3ml is 10mg/ml, so 5mg is 50 units. half the barrel, feels like a lot but its right
if the powder is on the stopper, tap it down before you add anything. it will still dissolve either way

nobody here should be telling you a dose. we can check your arithmetic, thats a different thing

the meniscus thing is real. read it at eye level or you are guessing by a unit either way

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nope, redo it

CO

coming back after 20 months, has the pinned recon volume advice changed

if i add 2.5ml to a 30mg vial what concentration am i actually at

i have never once regretted using a rounder number and a slightly bigger volume, your mileage will differ

TT

i keep a spare vial of bac water in the fridge purely so i never rush the maths

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can i add more bac water later to a vial ive already reconstituted

SS

is the meniscus reading actually a real source of error or am i overthinking

BR

if the powder is on the stopper, tap it down before you add anything. it will still dissolve either way

SS

anyone worked out a recon volume that puts 0.25mg on a round unit mark

fridge-temps.csv
336 rows · not retained in the public archive

ok so it should be completely clear with no floaters. cloudy means stop

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LL

follow up the vacuum will pull it in. let it. fighting it is how you get a face full of aerosol

dead space in a standard insulin syringe hub is small but it is not nothing over a month, someone check my working
update from 11 months ago: switched to a single concentration and have not miscalculated since

swirl it. do not shake it. the foam is denatured protein and you are not getting it back

quick one if you draw up with a bigger pin and inject with a fresh one you lose a bit more to dead space

a 3ml syringe for the diluent and a u100 for the dose is the setup most people here end up with

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DE

does benzyl alcohol matter if im finishing the vial in one go

thats the vacuum

pick the volume so your dose is a whole number of units. thats the entire trick, someone check my working

LM

temperature of the diluent does not matter. how fast you push it in does

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a slightly collapsed cake is cosmetic. a puddle in the bottom is not

DE

you can absolutely just always use 2ml, and honestly most of us should

DE

how much do i lose to dead space with a 29G pin

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LM

the jewellery scale is a good habit but calibrate it, they drift badly

LL

if you cannot read the mark confidently, your volume is too small. redo it at a lower concentration

i swirl for about thirty seconds and then leave it. never had one fail to dissolve

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DE

is it worth buying a 3ml syringe for the diluent or is the insulin one fine

bac water or sterile water for something im going into weekly for 2 weeks

LL

the last few units are a real loss. i accept it rather than tilting the vial and drawing air

DE

weighing the vial before you reconstitute is the only way to catch an underfill, not advice obviously

LL

5mg in 2ml gives 2.5mg/ml, 0.25mg is 10 units. good for a starting dose

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do you draw up with the same pin you inject with

VB

Archive lookup: deadspace first appears in this channel on 2025-12-01.

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