vialroom

#reconstitution 2025-07-21

Monday25 messages6 participantstimes are UTC
Highlights from this day
  • pin29g — if you draw up with a bigger pin and inject with a fresh one you lose a bit more to dead space bacteriostatic water for anything multi-use. sterile water has no… 20:58
  • oli_orals — label the date too. you will not remember which vial is which by week 21 21:29
  • rotterdam_recon — i was wrong about this last year: it is fine to draw cold, it just stings more going in 21:39
  • oli_orals — while im here lyophilised powder is far more robust than people think. it is the solution that is fragile, i think 22:27
  • pin29g — my rule is one concentration for everything so i never have to think about it at 7am, thats one data point 23:23
P2

the last few units are a real loss. i accept it rather than tilting the vial and drawing air

if you draw up with a bigger pin and inject with a fresh one you lose a bit more to dead space
bacteriostatic water for anything multi-use. sterile water has no preservative in it at all

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OB

does it matter if i inject the bac water straight at the powder

[edited]

the vacuum will pull it in. let it. fighting it is how you get a face full of aerosol

why does everyone say 2ml specifically and not 1ml

P2

thats fine

U-100 syringe: 1 unit = 0.01 ml
  10u = 0.10 ml
  25u = 0.25 ml
  50u = 0.50 ml
 100u = 1.00 ml
mg drawn = ml drawn x mg/ml
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anyone got a photo of what a properly dissolved vial looks like

OO

label the date too. you will not remember which vial is which by week 21

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RR

i was wrong about this last year: it is fine to draw cold, it just stings more going in

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OO

unrelated but benzyl alcohol is what makes it bacteriostatic. it is about 0.9% typically

P2

how do you all measure a half unit, or do you just not

P2

whats the smallest volume you would trust yourself to measure on a u100

OB

sorry to jump in does temperature of the bac water matter at all

[edited]
P2

i keep a spare vial of bac water in the fridge purely so i never rush the maths

OB

if the powder is on the stopper, tap it down before you add anything. it will still dissolve either way

P2

foam is bad

transit-times.csv
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my rule is one concentration for everything so i never have to think about it at 7am, thats one data point