vialroom

#reconstitution 2026-02-14

Saturday21 messages6 participantstimes are UTC
Highlights from this day
  • van_isle_vial — if you draw up with a bigger pin and inject with a fresh one you lose a bit more to dead space 18:48
  • lead_time_lars — dead space in a standard insulin syringe hub is small but it is not nothing over a month, someone check my working 19:07
  • pharmac_pen — my vial pulled the water in on its own, is that the vacuum or did i do something 19:42
  • lead_time_lars — a slightly collapsed cake is cosmetic. a puddle in the bottom is not 20:10

if you draw up with a bigger pin and inject with a fresh one you lose a bit more to dead space

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swirl it. do not shake it. the foam is denatured protein and you are not getting it back

LT

dead space in a standard insulin syringe hub is small but it is not nothing over a month, someone check my working

VI

sorry to jump in the last few units are a real loss. i accept it rather than tilting the vial and drawing air

PP

does it matter if i inject the bac water straight at the powder

check your maths

my vial pulled the water in on its own, is that the vacuum or did i do something

😂2🎉3
AO

5mg in 2ml gives 2.5mg/ml, 0.25mg is 10 units. good for a starting dose

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PP

anyone worked out a recon volume that puts 1mg on a round unit mark

the meniscus thing is real. read it at eye level or you are guessing by a unit either way

gross powder mass is not net peptide. water and counterion are in that number

PP

weighing the vial before you reconstitute is the only way to catch an underfill, anyway