too dilute imo
#reconstitution 2025-11-08
Saturday52 messages12 participantstimes are UTC
Highlights from this day
- split_shipment — is it normal for the cake to look slightly collapsed on one side 10:57
- triumph_watch — aim the diluent at the glass wall, not at the powder. it goes in gentler 13:56
- two_four_ceiling — can i add more bac water later to a vial ive already reconstituted 13:57
- impersonator_ip — dead space in a standard insulin syringe hub is small but it is not nothing over a month 14:40
sorry to jump in the last few units are a real loss. i accept it rather than tilting the vial and drawing air
coming back to this is there any reason not to just always use 2ml
update from 18 months ago: switched to a single concentration and have not miscalculated since
round numbers
not sterile water
my vial pulled the water in on its own, is that the vacuum or did i do something
foam is bad
unrelated but the jewellery scale is a good habit but calibrate it, they drift badly
coming back after 9 months, has the pinned recon volume advice changed
gross powder mass is not net peptide. water and counterion are in that number
dark_for_ten_daysunrelated but the jewellery scale is a good habit but calibrate it, they drift badly
anyone worked out a recon volume that puts 7.5mg on a round unit mark
dead space
weigh it first
anyone else find the 40mg vials harder to get fully dissolved than the small ones
slightly off topic but pick the volume so your dose is a whole number of units. thats the entire trick
you can absolutely just always use 2ml, and honestly most of us should
unrelated but swirl it. do not shake it. the foam is denatured protein and you are not getting it back
the vacuum will pull it in. let it. fighting it is how you get a face full of aerosol
i keep a spare vial of bac water in the fridge purely so i never rush the maths
is it normal for the cake to look slightly collapsed on one side
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thats fine
do you draw up with the same pin you inject with
label the vial
if the powder is on the stopper, tap it down before you add anything. it will still dissolve either way
write the date on
read it at eye level
why does everyone say 2ml specifically and not 1ml
bac water
label the date too. you will not remember which vial is which by week 33
swirl dont shake
coming back to this my rule is one concentration for everything so i never have to think about it at 7am
is it worth buying a 3ml syringe for the diluent or is the insulin one fine
a slightly collapsed cake is cosmetic. a puddle in the bottom is not
i was wrong about this last year: it is fine to draw cold, it just stings more going in, anyway
weighing the vial before you reconstitute is the only way to catch an underfill
check your maths
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while im here lyophilised powder is far more robust than people think. it is the solution that is fragile
thats 5mg/ml
how do you all measure a half unit, or do you just not
took me a year to stop over-diluting. the measurement error at 4 units is worse than the convenience
a 3ml syringe for the diluent and a u100 for the dose is the setup most people here end up with
aim the diluent at the glass wall, not at the powder. it goes in gentler
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can i add more bac water later to a vial ive already reconstituted
10mg vial
+ 1.0ml -> 10.0 mg/ml 0.5mg = 5u 1mg = 10u
+ 2.0ml -> 5.0 mg/ml 0.5mg = 10u 1mg = 20u
+ 2.5ml -> 4.0 mg/ml 0.5mg = 12.5u (dont)
+ 5.0ml -> 2.0 mg/ml 0.5mg = 25u 1mg = 50uupdate on the earlier thing is a slightly cloudy solution ever ok or is that always a bin it
sanity check my maths before i pin myself with something stupid
dead space in a standard insulin syringe hub is small but it is not nothing over a month
10mg vial
+ 1.0ml -> 10.0 mg/ml 0.5mg = 5u 1mg = 10u
+ 2.0ml -> 5.0 mg/ml 0.5mg = 10u 1mg = 20u
+ 2.5ml -> 4.0 mg/ml 0.5mg = 12.5u (dont)
+ 5.0ml -> 2.0 mg/ml 0.5mg = 25u 1mg = 50uthe powder is stuck to the stopper, do i care
20mg in 2ml is 10mg/ml. 1mg is 10 units, 2mg is 20 units, easy
follow up it should be completely clear with no floaters. cloudy means stop
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update on the earlier thing im getting bubbles in the barrel every single time, what am i doing wrong
quick one 5mg in 2ml gives 2.5mg/ml, 0.25mg is 10 units. good for a starting dose
update on the earlier thing update from 4 months ago: switched to a single concentration and have not miscalculated since, anyway