vialroom

#reconstitution 2026-05-09

Saturday29 messages7 participantstimes are UTC
Highlights from this day
  • fibre_first — my vial pulled the water in on its own, is that the vacuum or did i do something 21:25
  • fibre_first — 10mg in 1ml is 10mg/ml, so 2.5mg is 25 units. thats the one i use temperature of the diluent does not matter. how fast you push it in does 21:57
  • oasis_ola — the last few units are a real loss. i accept it rather than tilting the vial and drawing air 22:58
TT

it should be completely clear with no floaters. cloudy means stop, ill dig out the number

FF

my vial pulled the water in on its own, is that the vacuum or did i do something

❤️18🧊1
TT

lyophilised powder is far more robust than people think. it is the solution that is fragile

FF

if the powder is on the stopper, tap it down before you add anything. it will still dissolve either way

🧪4🤝4

temperature of the diluent does not matter. how fast you push it in does

DV

i use bac water even for a single-use vial because it stings less, which is not the reason it exists

FF

the vacuum will pull it in. let it. fighting it is how you get a face full of aerosol

SD

give it 3 minutes at room temperature before you decide it has not dissolved

GG

i was wrong about this last year: it is fine to draw cold, it just stings more going in

is there any reason not to just always use 2ml

FF

dead space in a standard insulin syringe hub is small but it is not nothing over a month

if you draw up with a bigger pin and inject with a fresh one you lose a bit more to dead space

❤️6

10mg in 1ml is 10mg/ml, so 2.5mg is 25 units. thats the one i use
temperature of the diluent does not matter. how fast you push it in does

🔥10💀11

a slightly collapsed cake is cosmetic. a puddle in the bottom is not

i keep a spare vial of bac water in the fridge purely so i never rush the maths

nobody here should be telling you a dose. we can check your arithmetic, thats a different thing

SD

coming back to this anyone worked out a recon volume that puts 12mg on a round unit mark

GG

whats the smallest volume you would trust yourself to measure on a u100

OO

i swirl for about thirty seconds and then leave it. never had one fail to dissolve

DV

if you cannot read the mark confidently, your volume is too small. redo it at a lower concentration

7❤️5

read it at eye level

update from 17 months ago: switched to a single concentration and have not miscalculated since

the jewellery scale is a good habit but calibrate it, they drift badly

OO

the last few units are a real loss. i accept it rather than tilting the vial and drawing air

10mg vial
  + 1.0ml  -> 10.0 mg/ml   0.5mg =  5u   1mg = 10u
  + 2.0ml  ->  5.0 mg/ml   0.5mg = 10u   1mg = 20u
  + 2.5ml  ->  4.0 mg/ml   0.5mg = 12.5u (dont)
  + 5.0ml  ->  2.0 mg/ml   0.5mg = 25u   1mg = 50u