aim the diluent at the glass wall, not at the powder. it goes in gentler, thats just me
#reconstitution 2026-04-19
Sunday40 messages8 participantstimes are UTC
Highlights from this day
- monoisotopic — sorry to jump in 15mg in 3ml is 5mg/ml. same numbers as 10 in 2, just more of it if you cannot read the mark confidently, your volume is too small. redo it at a lower… 18:30
- otto_swirls — if the powder is on the stopper, tap it down before you add anything. it will still dissolve either way 30mg in 3ml is 10mg/ml, so 5mg is 50 units. half the barrel,… 19:34
- sulphur_burp — unrelated but do you draw up with the same pin you inject with 19:51
- monoisotopic — my vial pulled the water in on its own, is that the vacuum or did i do something 20:22
sorry to jump in 15mg in 3ml is 5mg/ml. same numbers as 10 in 2, just more of it
if you cannot read the mark confidently, your volume is too small. redo it at a lower concentration
one unit is 0.01ml. 100 units is 1ml. everything else in this channel follows from that
dead space in a standard insulin syringe hub is small but it is not nothing over a month
coming back to this temperature of the diluent does not matter. how fast you push it in does
*VendorInvestigate not the other one
do not add more bac water to an already reconstituted vial, you have lost track of the concentration
quick one it should be completely clear with no floaters. cloudy means stop
for the archive i have never once regretted using a rounder number and a slightly bigger volume, thats just me
5mg in 2ml gives 2.5mg/ml, 0.25mg is 10 units. good for a starting dose
write the date on
i swirl for about thirty seconds and then leave it. never had one fail to dissolve
can i add more bac water later to a vial ive already reconstituted
the last few units are a real loss. i accept it rather than tilting the vial and drawing air, ill dig out the number
the jewellery scale is a good habit but calibrate it, they drift badly
nobody here should be telling you a dose. we can check your arithmetic, thats a different thing
i was wrong about this last year: it is fine to draw cold, it just stings more going in, not advice obviously
dead space
if you cannot read the mark confidently, your volume is too small. redo it at a lower concentration
im getting bubbles in the barrel every single time, what am i doing wrong
if the powder is on the stopper, tap it down before you add anything. it will still dissolve either way
30mg in 3ml is 10mg/ml, so 5mg is 50 units. half the barrel, feels like a lot but its right
weighing the vial before you reconstitute is the only way to catch an underfill
the vacuum will pull it in. let it. fighting it is how you get a face full of aerosol
is it normal for the cake to look slightly collapsed on one side
[edited]check your maths
yep 10 units
lyophilised powder is far more robust than people think. it is the solution that is fragile
do i swirl for a specific length of time or just until its clear
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my vial pulled the water in on its own, is that the vacuum or did i do something
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give it 5 minutes at room temperature before you decide it has not dissolved
i write the mg/ml on the vial with a sharpie the moment i reconstitute it
anyone else find the 40mg vials harder to get fully dissolved than the small ones
i keep a spare vial of bac water in the fridge purely so i never rush the maths, thats just me
not sterile water
one unit is 0.01ml
while im here what do you do with the last 40 units when you cant draw them cleanly
right so 30mg in 3ml is 10mg/ml, so 5mg is 50 units. half the barrel, feels like a lot but its right
does it matter if i inject the bac water straight at the powder
label the date too. you will not remember which vial is which by week 20