vialroom

#reconstitution 2026-06-26

Friday19 messages4 participantstimes are UTC
Highlights from this day
  • u100_pat — give it 4 minutes at room temperature before you decide it has not dissolved 16:19
  • rotterdam_recon — does temperature of the bac water matter at all 16:26
  • rotterdam_recon — is it normal for the cake to look slightly collapsed on one side 16:40
  • vale_vials — i was wrong about this last year: it is fine to draw cold, it just stings more going in 18:29
U1

lyophilised powder is far more robust than people think. it is the solution that is fragile

VV

slightly off topic but weighing the vial before you reconstitute is the only way to catch an underfill

20mg in 2ml is 10mg/ml. 1mg is 10 units, 2mg is 20 units, easy

U1

give it 4 minutes at room temperature before you decide it has not dissolved

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thats the vacuum

does temperature of the bac water matter at all

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RR

is it normal for the cake to look slightly collapsed on one side

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MP

can i add more bac water later to a vial ive already reconstituted

RR

i swirl for about thirty seconds and then leave it. never had one fail to dissolve

MP

do you let it come to room temp before drawing or draw it cold

i write the mg/ml on the vial with a sharpie the moment i reconstitute it

aim the diluent at the glass wall, not at the powder. it goes in gentler

VV

i was wrong about this last year: it is fine to draw cold, it just stings more going in

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