if the powder is on the stopper, tap it down before you add anything. it will still dissolve either way
#reconstitution 2026-05-29
Friday50 messages12 participantstimes are UTC
Highlights from this day
- mg_per_ml — update from 26 months ago: switched to a single concentration and have not miscalculated since, ill dig out the number 19:34
- sedge_sources — my rule is one concentration for everything so i never have to think about it at 7am 19:48
- sedge_sources — unrelated but my vial pulled the water in on its own, is that the vacuum or did i do something i keep a spare vial of bac water in the fridge purely so i never rush… 20:17
- non_scale_win — 5mg in 2ml gives 2.5mg/ml, 0.25mg is 10 units. good for a starting dose 20:24
i keep a spare vial of bac water in the fridge purely so i never rush the maths
lyophilised powder is far more robust than people think. it is the solution that is fragile, thats one data point
i was wrong about this last year: it is fine to draw cold, it just stings more going in, i have it written down somewhere
give it 2 minutes at room temperature before you decide it has not dissolved
coming back to this 20mg in 2ml is 10mg/ml. 1mg is 10 units, 2mg is 20 units, easy
one unit is 0.01ml
the vacuum will pull it in. let it. fighting it is how you get a face full of aerosol
*PeptideMeter not the other one
check your maths
peptidemeter-summary-d-0718.pdf
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pick the volume so your dose is a whole number of units. thats the entire trick
i use bac water even for a single-use vial because it stings less, which is not the reason it exists
does benzyl alcohol matter if im finishing the vial in one go
[edited]too dilute imo
nope, redo it
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label the date too. you will not remember which vial is which by week 25
my rule is one concentration for everything so i never have to think about it at 7am
i have never once regretted using a rounder number and a slightly bigger volume, thats just me
bac water or sterile water for something im going into weekly for 5 weeks
Digest for the week of 2026-01-23 has been published.
a slightly collapsed cake is cosmetic. a puddle in the bottom is not, i could be wrong
slightly off topic but nobody here should be telling you a dose. we can check your arithmetic, thats a different thing
dead space
weigh it first
10mg in 1ml is 10mg/ml, so 2.5mg is 25 units. thats the one i use
aim the diluent at the glass wall, not at the powder. it goes in gentler
update from 26 months ago: switched to a single concentration and have not miscalculated since, ill dig out the number
10mg vial
+ 1.0ml -> 10.0 mg/ml 0.5mg = 5u 1mg = 10u
+ 2.0ml -> 5.0 mg/ml 0.5mg = 10u 1mg = 20u
+ 2.5ml -> 4.0 mg/ml 0.5mg = 12.5u (dont)
+ 5.0ml -> 2.0 mg/ml 0.5mg = 25u 1mg = 50uone unit is 0.01ml. 100 units is 1ml. everything else in this channel follows from that
follow up dead space in a standard insulin syringe hub is small but it is not nothing over a month
do i swirl for a specific length of time or just until its clear
my rule is one concentration for everything so i never have to think about it at 7am
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if the maths gives you 13.7 units, change the volume. do not try to hit 13.7
swirl dont shake
can i add more bac water later to a vial ive already reconstituted
unrelated but my vial pulled the water in on its own, is that the vacuum or did i do something
i keep a spare vial of bac water in the fridge purely so i never rush the maths
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*that should say weekly
im getting bubbles in the barrel every single time, what am i doing wrong
10mg in 2ml is 5mg/ml. so 0.5mg is 0.1ml which is 10 units on a u100
5mg in 2ml gives 2.5mg/ml, 0.25mg is 10 units. good for a starting dose
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foam is bad
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why does everyone say 2ml specifically and not 1ml
bacteriostatic water for anything multi-use. sterile water has no preservative in it at all
my rule is one concentration for everything so i never have to think about it at 7am
the powder is stuck to the stopper, do i care
is the meniscus reading actually a real source of error or am i overthinking
if you draw up with a bigger pin and inject with a fresh one you lose a bit more to dead space
read it at eye level
sanity check my maths before i pin myself with something stupid
anyone worked out a recon volume that puts 5mg on a round unit mark
thats fine
label the vial
does temperature of the bac water matter at all