Topic
Tirzepatide
Page 8 of 15 — Dual GIP/GLP-1 agonism, the SURMOUNT and SURPASS trials, the 2.5 to 15mg ladder, and the argument about whether anyone needs the…
Messages — page 8 of 15
question_queuei went to 15 and came back to 10, more suppression wasnt more useful for me#tirzepatide · 2025-09-26cricket_or_footygenuine question appetite suppression at 0.5 was stronger than my tirzepatide experience at a comparable point, your mileage…#retatrutide · 2025-09-26bengaluru_bactirzepatide is about 4813.5 Da, so 2+ is near 2407.8 and 3+ near 1605.5#hplc-massspec · 2025-09-26snac_and_waterlow and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom#retatrutide · 2025-09-27cricket_or_footysorry to jump in GI was about the same as tirzepatide for me, the difference was how fast it arrived, ask me again in a month#retatrutide · 2025-09-27gus_chartsgenuine question appetite suppression at 1 was stronger than my tirzepatide experience at a comparable point#retatrutide · 2025-09-28triple_ag_tomthats the win#wins · 2025-09-28wren_weighs_in7.5 gang#tirzepatide · 2025-10-02lot_number_loudid the phase 2 result actually come in higher than the tirzepatide numbers#retatrutide · 2025-10-02steady_state_suefollow up is the GI worse than tirzepatide or about the same#retatrutide · 2025-10-02mira_pinslow and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom#retatrutide · 2025-10-02mira_pinsok so appetite suppression at 0.25 was stronger than my tirzepatide experience at a comparable point#retatrutide · 2025-10-02rotterdam_reconlow and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom#retatrutide · 2025-10-03retention_timeSURMOUNT-OSA — tirzepatide in obstructive sleep apnoea with obesity#wins · 2025-10-03retention_timethat trial is tirzepatide and im on sema, so mine is an anecdote, not a result. but the direction is not a surprise anymore#wins · 2025-10-03underfill_umathe powder itself takes up volume as well. 30mg of tirz is a visible cake#reconstitution · 2025-10-05tarpit_tammy titration ladder took 17 months to climb and i would do it slower again#dosing-titration · 2025-10-05area_percenttirzepatide is about 4813.5 Da, so 2+ is near 2407.8 and 3+ near 1605.5#hplc-massspec · 2025-10-05power_through_nolow and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom#retatrutide · 2025-10-06gradient_gregfor the archive tirzepatide is about 4813.5 Da, so 2+ is near 2407.8 and 3+ near 1605.5, for what its worth#hplc-massspec · 2025-10-08see_a_clinicianGI was about the same as tirzepatide for me, the difference was how fast it arrived, for what its worth#retatrutide · 2025-10-09egfr_edGI was about the same as tirzepatide for me, the difference was how fast it arrived#retatrutide · 2025-10-11dexa_or_biaalt and ast coming down as you lose liver fat is common and is a good sign#bloodwork · 2025-10-11thirty_min_waitfollow up GI was about the same as tirzepatide for me, the difference was how fast it arrived, we shall see#retatrutide · 2025-10-12bea_reconstitutestirzepatide is about 4813.5 Da, so 2+ is near 2407.8 and 3+ near 1605.5#hplc-massspec · 2025-10-12area_percentback after 8 months, do i restart at 2.5 or pick up near where i left off#tirzepatide · 2025-10-13careful_claimsslow is fine#wins · 2025-10-13food_noise_offdid the phase 2 result actually come in higher than the tirzepatide numbers#retatrutide · 2025-10-14ghent_gradienttirzepatide is about 4813.5 Da, so 2+ is near 2407.8 and 3+ near 1605.5#hplc-massspec · 2025-10-14slow.taperis the GI worse than tirzepatide or about the same#retatrutide · 2025-10-15warsaw_viallow and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom stepping in 2.5 increments…#retatrutide · 2025-10-16point_two_fiveis the GI worse than tirzepatide or about the same#retatrutide · 2025-10-17gus_chartsappetite suppression at 2.4 was stronger than my tirzepatide experience at a comparable point#retatrutide · 2025-10-17stack_scepticlow and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom#retatrutide · 2025-10-17belfast_bacthe two compounds arent interchangeable week for week even if the effect ends up similar#tirzepatide · 2025-10-18half_life_haltitrate slow#tirzepatide · 2025-10-19thirty_min_waitSURMOUNT-OSA was the sleep apnoea trial and it is not a weight headline however its quoted, from memory#tirzepatide · 2025-10-20wren_weighs_inis the GI worse than tirzepatide or about the same#retatrutide · 2025-10-20apnoea_down_twook so low and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom#retatrutide · 2025-10-21batch_banditappetite suppression at 15 was stronger than my tirzepatide experience at a comparable point, thats just me#retatrutide · 2025-10-21invoice_mismatchwhats a realistic amount of regain to accept rather than panic about#maintenance · 2025-10-21fridge_thermoslower worked better#semaglutide · 2025-10-22two_four_ceilingtirzepatide is about 4813.5 Da, so 2+ is near 2407.8 and 3+ near 1605.5#hplc-massspec · 2025-10-23adelaide_assaychanged my mind about needing 15, i was chasing a number rather than an outcome#tirzepatide · 2025-10-25food_noise_offsorry to jump in appetite suppression at 5 was stronger than my tirzepatide experience at a comparable point#retatrutide · 2025-10-25slow.taperlow and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom#retatrutide · 2025-10-25deadspacelow and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom#retatrutide · 2025-10-27tokyo_taperGI was about the same as tirzepatide for me, the difference was how fast it arrived#retatrutide · 2025-10-27ruo_onlyfollow up anyone gone from 12 straight to 0.5 or is that too big a jump#semaglutide · 2025-10-28weather_watchdid the phase 2 result actually come in higher than the tirzepatide numbers#retatrutide · 2025-10-29turnaround_tamis the GI worse than tirzepatide or about the same#retatrutide · 2025-10-29no_escrow_natesorry to jump in appetite suppression at 2.4 was stronger than my tirzepatide experience at a comparable point#retatrutide · 2025-11-01no_escrow_natelow and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom#retatrutide · 2025-11-01HPLC_Hanksorry to jump in tirzepatide is about 4813.5 Da, so 2+ is near 2407.8 and 3+ near 1605.5, take that with a pinch of salt#hplc-massspec · 2025-11-01nausea_windowappetite suppression at 15 was stronger than my tirzepatide experience at a comparable point#retatrutide · 2025-11-04orfor_watchtirzepatide is about 4813.5 Da, so 2+ is near 2407.8 and 3+ near 1605.5#hplc-massspec · 2025-11-04glasgow_vialfor the archive appetite suppression at 1.7 was stronger than my tirzepatide experience at a comparable point#retatrutide · 2025-11-06auckland_aliquotdid the phase 2 result actually come in higher than the tirzepatide numbers#retatrutide · 2025-11-06glasgow_vialis the GI worse than tirzepatide or about the same#retatrutide · 2025-11-06taste_changedfor the archive GI was about the same as tirzepatide for me, the difference was how fast it arrived#retatrutide · 2025-11-08