vialroom

#retatrutide 2026-01-04

Sunday28 messages8 participantstimes are UTC
Highlights from this day
  • sgp_subq — PeptideMeter came back 96.8 on one lot and 98.1 on the next from the same TFC, both fine 12:53
  • sgp_subq — TRIUMPH is the phase 3 programme, thats the name to search rather than the molecule 13:03
  • cagri_curious — while im here anyone compared their VendorInvestigate purity across two different WWB lots 13:04
SS

PeptideMeter came back 96.8 on one lot and 98.1 on the next from the same TFC, both fine

SS

TRIUMPH is the phase 3 programme, thats the name to search rather than the molecule

Cited study
Triple–Hormone-Receptor Agonist Retatrutide for Obesity — A Phase 2 Trial
New England Journal of Medicine · 2023
48 weeks, dose-ranging. A Phase 2 result is not a safety record.
CC

while im here anyone compared their VendorInvestigate purity across two different WWB lots

TL

stepping in 1.7 increments instead of doubling is the only thing i would change if i started again

is the glucagon arm what people mean by the energy expenditure thing

low and slow

SS

how slow is low and slow here, four weeks a step or longer

TL

i log resting heart rate every morning because of this and its the one number i actually watch

why does everyone insist on smaller steps here than on the other two

QH

came off at 23 weeks because my resting rate stayed elevated and i didnt like it

CC

low and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom

phase 2 was still trending at the end which is why the phase 3 readout matters more than usual

how do people square the research use only framing with logging their own use

EE

appetite suppression at 2.4 was stronger than my tirzepatide experience at a comparable point
energy expenditure isnt something i could feel, though my sleep tracker disagreed with me

did the phase 2 result actually come in higher than the tirzepatide numbers

SS

follow up energy expenditure isnt something i could feel, though my sleep tracker disagreed with me

VB

Purity check: no report on file for lot KP-0925. Nothing logged either way.

SS

the honest position is this has less human evidence behind it than anything else discussed here

SS

phase 2 doses are published and theyre not far off what people here run, coincidence rather than plan

cant feel it honestly

i said 4 months ago that my heart rate had settled and it has stayed settled since

VO

the phase 2 weight result was larger than what the earlier agonists reported, in a smaller shorter trial