logging rhr daily
#retatrutide 2026-01-30
Friday42 messages9 participantstimes are UTC
Highlights from this day
- adelaide_assay — is the glucagon arm what people mean by the energy expenditure thing 15:53
- VialBot — Inter-lab diff for lot C-4402: 97.4% vs 99%. Within expected range. 17:03
- nordic_price_nils — anyone compared their Janoshik purity across two different QST lots 17:22
- VialBot — Reminder for lot_number_lou: dose day is today. Set 5 days ago. 19:09
- cass_cagri — Janoshik came back 99.4 on one lot and 98.1 on the next from the same BCH, both fine 19:22
watching my heart rate
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the glucagon arm is the mechanistic story for extra energy expenditure and its still a story to me
the heart rate thing is real enough that i mention it whenever someone asks about starting
anyone stayed at 10 for months rather than climbing
is the glucagon arm what people mean by the energy expenditure thing
baseline 58
wk 2 61
wk 4 64
wk 6 67
wk 8 66
wk 10 65 (held dose from wk 7)held mine ages
settled by month three
came off at 9 weeks because my resting rate stayed elevated and i didnt like it
the honest position is this has less human evidence behind it than anything else discussed here
phase 2 was still trending at the end which is why the phase 3 readout matters more than usual
the phase 2 weight result was larger than what the earlier agonists reported, in a smaller shorter trial
coming back to this no idea whether the heart rate settles for everyone, mine did and one log isnt data
[edited]triple agonist meaning GLP-1, GIP and glucagon, have i got that right
mine went up too
did the phase 2 result actually come in higher than the tirzepatide numbers
*Medutest not the other one
TRIUMPH is phase 3
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research use only
energy expenditure isnt something i could feel, though my sleep tracker disagreed with me
TRIUMPH is the phase 3 programme, thats the name to search rather than the molecule
my resting heart rate is up about 8 bpm, did that settle for anyone
Inter-lab diff for lot C-4402: 97.4% vs 99%. Within expected range.
anyone compared their Janoshik purity across two different QST lots
smaller steps here
how long before people saw the first change at 0.5
the honest position is this has less human evidence behind it than anything else discussed here, someone check my working
how slow is low and slow here, four weeks a step or longer
is TRIUMPH the phase 3 programme
whats the half life like, is it weekly the same way
did the phase 2 plateau or was it still moving at the end
whats a sensible starting point, im seeing everything from 0.5 to 2
i said 5 months ago that my heart rate had settled and it has stayed settled since
cant feel it honestly
there is no long term safety data, phase 2 and an ongoing phase 3 programme is what exists
*PeptideMeter not the other one
Reminder for lot_number_lou: dose day is today. Set 5 days ago.
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lost 20kg over 24 months at doses well under what the trials used, still working it out
anyone logging resting heart rate on this
Janoshik came back 99.4 on one lot and 98.1 on the next from the same BCH, both fine
people insist on small steps because the side effects arrive faster than on the other two
blood pressure stayed flat for me while heart rate moved, which i didnt expect