Topic
Tirzepatide
Page 10 of 15 — Dual GIP/GLP-1 agonism, the SURMOUNT and SURPASS trials, the 2.5 to 15mg ladder, and the argument about whether anyone needs the…
Messages — page 10 of 15
u100_patdid the phase 2 result actually come in higher than the tirzepatide numbers#retatrutide · 2025-12-14mag_citratei log everything and my appetite curve looks flatter across the week than my semaglutide log did no gap when i switched, took…#tirzepatide · 2025-12-15reading_the_pinsthe report says retention time matches the standard so it is confirmed as tirzepatide. that seems solid to me?#hplc-massspec · 2025-12-17monoisotopicit is consistent with tirzepatide. it is not confirmation of tirzepatide#hplc-massspec · 2025-12-17void_volumelike this#hplc-massspec · 2025-12-17customs_owldid the STEP 4 withdrawal arm show what i think it showed#semaglutide · 2025-12-19tail_factoris the GI worse than tirzepatide or about the same#retatrutide · 2025-12-19oasis_olalow and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom, thats just me#retatrutide · 2025-12-19site_itchlow and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom#retatrutide · 2026-01-03cagri_curiousis the GI worse than tirzepatide or about the same#retatrutide · 2026-01-04cagri_curiouslow and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom#retatrutide · 2026-01-04electrolyte_elidid the phase 2 result actually come in higher than the tirzepatide numbers#retatrutide · 2026-01-04rotate_the_sitefor the archive tirzepatide is about 4813.5 Da, so 2+ is near 2407.8 and 3+ near 1605.5 co-elution is the failure mode that a…#hplc-massspec · 2026-01-04pharmac_penlicensed top is 15 weekly, past that is not a licensed dose and nobody here can tell you what it does#tirzepatide · 2026-01-06void_volumetirzepatide is about 4813.5 Da, so 2+ is near 2407.8 and 3+ near 1605.5, n of 1 obviously#hplc-massspec · 2026-01-06cedar_countsstart low anyway#tirzepatide · 2026-01-07LC_MS_Lenawent back to semaglutide after 8 months because the cost difference mattered more than the GI#tirzepatide · 2026-01-07first_and_last_fourdid the phase 2 result actually come in higher than the tirzepatide numbers#retatrutide · 2026-01-10first_and_last_fouris the GI worse than tirzepatide or about the same#retatrutide · 2026-01-10lisbon_lotGI was about the same as tirzepatide for me, the difference was how fast it arrived#retatrutide · 2026-01-10slow.taperif the current dose is still working, going up is spending headroom you might want later#dosing-titration · 2026-01-11cold_chain_cmdrtirzepatide is about 4813.5 Da, so 2+ is near 2407.8 and 3+ near 1605.5#hplc-massspec · 2026-01-11back_from_awayappetite suppression at 0.25 was stronger than my tirzepatide experience at a comparable point#retatrutide · 2026-01-12vial_ledgeris the GI worse than tirzepatide or about the same#retatrutide · 2026-01-12lipase_loredid anyone hold at 5 longer than four weeks before going up#semaglutide · 2026-01-13orfor_watchis the GI worse than tirzepatide or about the same#retatrutide · 2026-01-13orfor_watchappetite suppression at 1.7 was stronger than my tirzepatide experience at a comparable point#retatrutide · 2026-01-13kev_measuresok so GI was about the same as tirzepatide for me, the difference was how fast it arrived#retatrutide · 2026-01-14seven_five_sweethow do you decide between holding and stepping when both feel wrong#dosing-titration · 2026-01-14salt_bridgethere have been vials that assayed as tirzepatide, vials that assayed as nothing much, and one memorable lot that was a GLP-1…#retatrutide · 2026-01-16typosquat_taylow and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom#retatrutide · 2026-01-17deadspaceis the GI worse than tirzepatide or about the same#retatrutide · 2026-01-17typosquat_tayappetite suppression at 0.25 was stronger than my tirzepatide experience at a comparable point, happy to be corrected#retatrutide · 2026-01-17tyne_tracksis the GI worse than tirzepatide or about the same#retatrutide · 2026-01-18tyne_tracksGI was about the same as tirzepatide for me, the difference was how fast it arrived#retatrutide · 2026-01-18warsaw_vialsorry to jump in did the phase 2 result actually come in higher than the tirzepatide numbers#retatrutide · 2026-01-21dublin_doseGI was about the same as tirzepatide for me, the difference was how fast it arrived#retatrutide · 2026-01-21reta_resting_hrlow and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom#retatrutide · 2026-01-21rezept_rolfi tried to come down and could not hold it, went back to treatment dose, and stopped apologising for it#maintenance · 2026-01-21slow.taperprovisional then, shout if a slot is wrong#lab-requests · 2026-01-22VialBottesting queue updated#lab-requests · 2026-01-22noct.titrateappetite suppression at 2.4 was stronger than my tirzepatide experience at a comparable point TRIUMPH is the phase 3…#retatrutide · 2026-01-23fibre_firstsorry to jump in is the GI worse than tirzepatide or about the same#retatrutide · 2026-01-23two_eight_choma-ir is fasting glucose times fasting insulin over a constant. the constant differs by unit system#bloodwork · 2026-01-23thank_you_year_ontitrate slow#tirzepatide · 2026-01-24ring_size_downGI was about the same as tirzepatide for me, the difference was how fast it arrived#retatrutide · 2026-01-24seoul_swirlgenuine question appetite suppression at 15 was stronger than my tirzepatide experience at a comparable point#retatrutide · 2026-01-24hot_mailboxfollow up low and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom#retatrutide · 2026-01-24snac_and_waterlab error maybe#bloodwork · 2026-01-24back_from_awayGI was about the same as tirzepatide for me, the difference was how fast it arrived people insist on small steps because the…#retatrutide · 2026-01-25triumph_watchis the GI worse than tirzepatide or about the same#retatrutide · 2026-01-25tb500_tobiastirzepatide is about 4813.5 Da, so 2+ is near 2407.8 and 3+ near 1605.5#hplc-massspec · 2026-01-25closer_not_simplerlow and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom#retatrutide · 2026-01-26declared_valueno clean conversion#tirzepatide · 2026-01-27igf_one_ivythats noise#dosing-titration · 2026-01-28otto_swirlsGI was about the same as tirzepatide for me, the difference was how fast it arrived#retatrutide · 2026-01-29two_four_ceilingthats not showing off#wins · 2026-01-29mcg_not_mgdid the phase 2 result actually come in higher than the tirzepatide numbers#retatrutide · 2026-01-30assay_not_puritytirzepatide is about 4813.5 Da, so 2+ is near 2407.8 and 3+ near 1605.5#hplc-massspec · 2026-01-31tail_factortirzepatide is about 4813.5 Da, so 2+ is near 2407.8 and 3+ near 1605.5#hplc-massspec · 2026-02-01