vialroom

#retatrutide 2026-01-05

Monday13 messages5 participantstimes are UTC
Highlights from this day
  • private_script_pri — the phase 2 weight result was larger than what the earlier agonists reported, in a smaller shorter trial 21:40
  • ferritin_fay — i went up too fast, got a fortnight of nothing but nausea, and dropped back two steps 21:52
  • two_lifts_a_week — TRIUMPH is the phase 3 programme, thats the name to search rather than the molecule, not advice obviously the glucagon arm is the mechanistic story for extra energy… 22:33
  • two_lifts_a_week — i log resting heart rate every morning because of this and its the one number i actually watch, from memory 22:44
  • madrid_mg — ok so nobody should read my log as a plan, im recording what i did and thats all it is, not advice obviously 22:46
PS

the phase 2 weight result was larger than what the earlier agonists reported, in a smaller shorter trial

FF

i went up too fast, got a fortnight of nothing but nausea, and dropped back two steps

🔥13

research use only is on every vial and i treat it as exactly that, nobody here is prescribing

TL

TRIUMPH is the phase 3 programme, thats the name to search rather than the molecule, not advice obviously
the glucagon arm is the mechanistic story for extra energy expenditure and its still a story to me

TL

i was wrong to call the heart rate a non issue last year, enough people logged it that i changed my mind

i log resting heart rate every morning because of this and its the one number i actually watch, from memory

1

mine went up too

MM

ok so nobody should read my log as a plan, im recording what i did and thats all it is, not advice obviously

Cited study
Triple–Hormone-Receptor Agonist Retatrutide for Obesity — A Phase 2 Trial
New England Journal of Medicine · 2023
48 weeks, dose-ranging. A Phase 2 result is not a safety record.
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