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#retatrutide 2026-02-09

Monday26 messages5 participantstimes are UTC
Highlights from this day
  • unsolicited_dm — TRIUMPH is the phase 3 programme, thats the name to search rather than the molecule, take that with a pinch of salt 20:22
  • tb500_tobias — anyone compared their VendorInvestigate purity across two different FGP lots 20:53
  • quiet_head_qi — coming back to this research use only is on every vial and i treat it as exactly that, nobody here is prescribing 21:39
  • quiet_head_qi — sorry to jump in whats a sensible starting point, im seeing everything from 0.5 to 2 22:44
TO

genuine question back after 19 months, has anything actually been published since

the purity spread across lots worries me more than the molecule does

CC

triple agonist yeah

fridge-temps.csv
526 rows · not retained in the public archive
QH

follow up did the phase 2 result actually come in higher than the tirzepatide numbers

👍11🔥1

no long term data

UD

stopped for 26 months and restarted at half my old dose, the ramp was easier second time

low and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom

UD

the heart rate thing is real enough that i mention it whenever someone asks about starting

phase 2 was still trending at the end which is why the phase 3 readout matters more than usual

i was wrong to call the heart rate a non issue last year, enough people logged it that i changed my mind
energy expenditure isnt something i could feel, though my sleep tracker disagreed with me

anyone compared their VendorInvestigate purity across two different FGP lots

📈6🧊6
QH

coming back to this research use only is on every vial and i treat it as exactly that, nobody here is prescribing

📈4👀12
UD

triple agonist, GLP-1 and GIP and glucagon. the glucagon arm is the part with no long history

lost 48kg over 7 months at doses well under what the trials used

QH

sorry to jump in whats a sensible starting point, im seeing everything from 0.5 to 2

👀8📈13
QH

the half life supports weekly dosing and thats what ive done from the start