anyone reconstituting 15 vials to 2 so the steps come out smaller
#retatrutide 2026-04-19
Sunday31 messages8 participantstimes are UTC
Highlights from this day
- thyroid_thea — anyone tracking blood pressure alongside the heart rate 22:22
- VialBot — Inter-lab diff for lot D-0718: 96.8% vs 99.2%. Within expected range. 22:48
- gip_glp_gil — anyone stayed at 0.25 for months rather than climbing 23:00
- rezept_rolf — i was wrong to call the heart rate a non issue last year, enough people logged it that i changed my mind 23:07
- rezept_rolf — phase 2 doses are published and theyre not far off what people here run, coincidence rather than plan 23:10
anyone tracking blood pressure alongside the heart rate
📈18😂7
held mine ages
ok so i went up too fast, got a fortnight of nothing but nausea, and dropped back two steps
my resting rate went up 3 bpm in the first month and came back most of the way by month 20
cant feel it honestly
whats the half life like, is it weekly the same way
settled by month three
phase 2 was still trending at the end which is why the phase 3 readout matters more than usual
does the glucagon arm explain the heart rate or is that unrelated
TRIUMPH is phase 3
logging rhr daily
is the glucagon arm what people mean by the energy expenditure thing
Inter-lab diff for lot D-0718: 96.8% vs 99.2%. Within expected range.
✅11⚠️13
mine went up too
anyone logging resting heart rate on this
anyone stayed at 0.25 for months rather than climbing
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the phase 2 weight result was larger than what the earlier agonists reported, in a smaller shorter trial
i was wrong to call the heart rate a non issue last year, enough people logged it that i changed my mind
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phase 2 doses are published and theyre not far off what people here run, coincidence rather than plan
🔥6👀13
right so is there any long term safety data at all or is it phase 2 and hope
sat at 2 for 7 months rather than climbing and it kept working, so i never went up
did the phase 2 plateau or was it still moving at the end
unrelated but energy expenditure isnt something i could feel, though my sleep tracker disagreed with me
for the archive anyone compared their PeptideMeter purity across two different MKM lots
appetite suppression at 2.4 was stronger than my tirzepatide experience at a comparable point
stopped for 23 months and restarted at half my old dose, the ramp was easier second time
no long term data
the glucagon arm is the mechanistic story for extra energy expenditure and its still a story to me
low and slow
low and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom