quick one back after 23 months, do i restart at 2.5 or pick up near where i left off
#tirzepatide 2026-03-28
Saturday41 messages9 participantstimes are UTC
Highlights from this day
£185 for a 15 vial is roughly what ive paid for the last year
the GIP explanation for easier nausea is plausible and i still treat it as a story not a fact
at 10 my appetite is gone entirely, did anyone go down rather than up
changed my mind about needing 15, i was chasing a number rather than an outcome
switched last year
slightly off topic but whats the plateau pattern here, same as semaglutide or different
checked the units twice
7.5 gang
the 2.5 to 5 step was the roughest one for me and everything after was easier
how long before the dual thing was noticeable to you
the sweet spot argument is really about effect per side effect, not a magic number, happy to be corrected
titrate slow
coming off semaglutide, is there a conversion or do i restart at 2.5
there is no clean conversion between the two, anyone giving you a ratio is guessing
while im here plateaued at 21 weeks the same way i did on semaglutide, so i doubt its compound specific
10 was enough
at 2.4 my appetite went completely and i dropped back a step, eating nothing isnt a win
while im here whats the top licensed dose, 15 or does it go higher
| Trial schedule | What most people here do | |
|---|---|---|
| Step interval | 4 weeks, fixed | 4-12 weeks, on symptoms |
| Holding | protocol deviation | normal and expected |
| Top dose | reached by design | often never reached |
| Coming down | not studied | common at maintenance |
anyone tracked whether the GI difference held at the top doses
is the 5 vial the common one or do people use 40
[edited]i argued the sweet spot was nonsense and then spent 21 months at 7.5 not needing more
start low anyway
15 is the top
🎉1🙏3📈1
my Janoshik result on a WXT vial came in at 99 which is why i keep buying from them, ask me again in a month
folklore probably
dual agonist, GIP as well as GLP-1, thats the whole difference in one line
right so did anybody switch back to semaglutide after trying this
[edited]easier gi for me
does the GIP arm actually explain the easier nausea or is that hand waving
same plateau here
ok so im at 1 and thinking about 0.25, did anyone gain anything from that step
5 did nothing
no gap when i switched, took the last semaglutide dose and started this a week later
❤️5😂10🤝17
GIP plus GLP-1
❤️1
how did people handle the 2.5 to 5 jump
quick one held 10 for 20 months and lost 35kg over that stretch, slow and boring and fine
i went to 15 and came back to 10, more suppression wasnt more useful for me
is the sweet spot argument about effect or about side effects
SURMOUNT is weight