im at 15 and thinking about 12, did anyone gain anything from that step
#tirzepatide 2026-04-06
Monday23 messages6 participantstimes are UTC
Highlights from this day
- manila_meniscus — is the sweet spot argument about effect or about side effects 17:13
- gall_bladder_gav — the switch felt like a step down at first and then caught up around week 25 18:13
- knees_first — the two compounds arent interchangeable week for week even if the effect ends up similar, i think 18:19
- gall_bladder_gav — how did people handle the 2.5 to 5 jump 18:56
back after 19 months, do i restart at 2.5 or pick up near where i left off
did anyone find the GI easier than semaglutide at an equivalent effect
no clean conversion
is the sweet spot argument about effect or about side effects
🎉12📉5❤️14
held 10 for 25 months and lost 16kg over that stretch, slow and boring and fine
is there a reason to titrate slower than the four week schedule
at 15 the GI came back for me, so my easier profile claim only applies below that
SURMOUNT is weight
the switch felt like a step down at first and then caught up around week 25
👀10📈3
while im here SURMOUNT-OSA was the sleep apnoea trial and it is not a weight headline however its quoted
the two compounds arent interchangeable week for week even if the effect ends up similar, i think
💀15📉17❤️6
18:21marrow.mod pinned a message
quick one why does everyone talk about 7.5 and not 10
SURMOUNT-1 versus SURPASS-2, which one was the weight trial
easier gi for me
12 did nothing extra over 10 for me and that still holds a year later
✅2📈1
5 did nothing
15 is the top
how did people handle the 2.5 to 5 jump
💀14
folklore probably
wk 1-4 2.5mg
wk 5-8 5.0mg
wk 9-20 7.5mg <- stayed here
wk 21-24 10.0mg (no extra benefit for me)
wk 25+ 7.5mg (came back down)genuine question i went to 15 and came back to 10, more suppression wasnt more useful for me
Inter-lab diff for lot E-2205: 97.4% vs 98.1%. Within expected range.