does the glucagon arm explain the heart rate or is that unrelated
#retatrutide 2026-04-10
Friday33 messages8 participantstimes are UTC
Highlights from this day
- mag_citrate — whats the half life like, is it weekly the same way 19:52
- plus_sixteen — sorry to jump in anyone compared their Janoshik purity across two different HJ lots 20:19
- non_scale_win — slightly off topic but appetite suppression at 0.5 was stronger than my tirzepatide experience at a comparable point 20:27
- a1c_lag — back after 4 months, has anything actually been published since 21:54
- bram_begins — there is no long term safety data, phase 2 and an ongoing phase 3 programme is what exists 22:21
whats the half life like, is it weekly the same way
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phase 2 only
came off at 20 weeks because my resting rate stayed elevated and i didnt like it
triple agonist yeah
low and slow
sorry to jump in anyone compared their Janoshik purity across two different HJ lots
slightly off topic but appetite suppression at 0.5 was stronger than my tirzepatide experience at a comparable point
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reconstituted the 5 vial to 8mg/ml specifically so i could take 2.5 without measuring crumbs
low and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom
TRIUMPH is the phase 3 programme, thats the name to search rather than the molecule
research use only
TRIUMPH is the phase 3 programme, thats the name to search rather than the molecule, take that with a pinch of salt
watching my heart rate
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did anyone come off because of the heart rate
stepping in 0.25 increments instead of doubling is the only thing i would change if i started again, i could be wrong
the honest position is this has less human evidence behind it than anything else discussed here
mine went up too
no long term data
i log resting heart rate every morning because of this and its the one number i actually watch, i think
how long before people saw the first change at 0.25
back after 4 months, has anything actually been published since
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buying this is a completely different risk conversation from the licensed compounds and that gets said too rarely
for the archive i went up too fast, got a fortnight of nothing but nausea, and dropped back two steps, your mileage will differ
cant feel it honestly
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unrelated but is the glucagon arm what people mean by the energy expenditure thing
there is no long term safety data, phase 2 and an ongoing phase 3 programme is what exists
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people insist on small steps because the side effects arrive faster than on the other two
follow up did the phase 2 plateau or was it still moving at the end
logging rhr daily
the half life supports weekly dosing and thats what ive done from the start
my resting heart rate is up about 2 bpm, did that settle for anyone
is the phase 2 dosing anywhere near what people here run
settled by month three