steady state takes weeks
#semaglutide 2026-04-27
Monday16 messages5 participantstimes are UTC
Highlights from this day
- egfr_ed — did anybody find a difference between TFC and pharmacy at the same 0.5 18:27
- area_percent — coming back to this FLOW was the kidney outcomes trial and it gets quoted in here for things it didnt measure 19:26
- area_percent — steady state is the bit people skip, judging a new dose after eight days tells you almost nothing 19:32
- area_percent — went 1 to 1.7 too fast and spent two weeks regretting it, dropped back and repeated the step, ask me again in a month 19:47
- area_percent — i held at 5 for 7 months and it was the best decision i made 20:38
did anybody find a difference between TFC and pharmacy at the same 0.5
transit-times.csv
740 rows · not retained in the public archive
🧪1
seven days ish
is 2.4 the top or do people go past it
[edited]plateaus move
same dose day
🔥5
coming back to this FLOW was the kidney outcomes trial and it gets quoted in here for things it didnt measure
🎉3🧊9
held at 5 and lost 99lb over 18 months, slower than the trials and fine by me
steady state is the bit people skip, judging a new dose after eight days tells you almost nothing
| Trial schedule | What most people here do | |
|---|---|---|
| Step interval | 4 weeks, fixed | 4-12 weeks, on symptoms |
| Holding | protocol deviation | normal and expected |
| Top dose | reached by design | often never reached |
| Coming down | not studied | common at maintenance |
went 1 to 1.7 too fast and spent two weeks regretting it, dropped back and repeated the step, ask me again in a month
🙏8🧪12👀16
thats STEP 1
Batch lookup G-0641: 4 independent reports on file, earliest 2026-02-11.
slower worked better
i held at 5 for 7 months and it was the best decision i made
| Trial schedule | What most people here do | |
|---|---|---|
| Step interval | 4 weeks, fixed | 4-12 weeks, on symptoms |
| Holding | protocol deviation | normal and expected |
| Top dose | reached by design | often never reached |
| Coming down | not studied | common at maintenance |
does the seven day half life mean the last two days are weaker
Reminder for split_the_cost: dose day is today. Set 6 days ago.