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Cagrilintide and amylin

Page 6 of 12 — Amylin analogues alone and in combination, why the titration wants to be slower than people expect, and a nausea profile most…

Messages — page 6 of 12

third_shift[redacted at member request]#cagrilintide · 2025-10-10ghent_gradientits an amylin analogue, different receptor family, so treating it as another GLP-1 is the first mistake#cagrilintide · 2025-10-10night_pinslightly off topic but held at 2 for 6 months on monotherapy before i touched it again, someone check my working#cagrilintide · 2025-10-10third_shiftslightly off topic but CagriSema is cagrilintide with semaglutide and REDEFINE is the trial programme around it#cagrilintide · 2025-10-10vat_on_importchanged my mind on this, i started thinking amylin was the interesting bit and now i think its the pairing#cagrilintide · 2025-10-12vat_on_importchanged my mind on this, i started thinking amylin was the interesting bit and now i think its the pairing#cagrilintide · 2025-10-12adelaide_assayhow slow are people titrating this compared to semaglutide#cagrilintide · 2025-10-12private_script_priamylin not glp-1#cagrilintide · 2025-10-13two_labs_two_answersamylin not glp-1#cagrilintide · 2025-10-14one_data_pointCagriSema is cagrilintide with semaglutide and REDEFINE is the trial programme around it#cagrilintide · 2025-10-14deadspacechanged my mind on this, i started thinking amylin was the interesting bit and now i think its the pairing#cagrilintide · 2025-10-14taper_tessits an amylin analogue, different receptor family, so treating it as another GLP-1 is the first mistake, anyway#cagrilintide · 2025-10-14ollie_ordersCagriSema is cagrilintide with semaglutide and REDEFINE is the trial programme around it, someone check my working#cagrilintide · 2025-10-15eight_mmamylin analogue, so its not a GLP-1 at all right#cagrilintide · 2025-10-17eight_mmCagriSema is cagrilintide with semaglutide and REDEFINE is the trial programme around it#cagrilintide · 2025-10-17tokyo_taperits an amylin analogue, different receptor family, so treating it as another GLP-1 is the first mistake, we shall see#cagrilintide · 2025-10-18tokyo_taperdoes amylin do something about fullness that the GLP-1 doesnt#cagrilintide · 2025-10-18tokyo_taperthe slower titration in here is community habit as much as anything, the trials had their own schedule, not advice obviously#cagrilintide · 2025-10-18snac_and_waterCagriSema is cagrilintide with semaglutide and REDEFINE is the trial programme around it#cagrilintide · 2025-10-19protein_floordoes amylin do something about fullness that the GLP-1 doesnt#cagrilintide · 2025-10-19meal_prep_mickquick one changed my mind on this, i started thinking amylin was the interesting bit and now i think its the pairing, anyway#cagrilintide · 2025-10-19meal_prep_mickamylin not glp-1#cagrilintide · 2025-10-19noct.titratedoes amylin do something about fullness that the GLP-1 doesnt#cagrilintide · 2025-10-21noct.titrateamylin is about slowed gastric emptying and satiety signalling, thats the short version and im no pharmacologist#cagrilintide · 2025-10-21question_queuefollow up amylin analogue, so its not a GLP-1 at all right#cagrilintide · 2025-10-21first_and_last_fourchanged my mind on this, i started thinking amylin was the interesting bit and now i think its the pairing, i could be wrong#cagrilintide · 2025-10-21first_and_last_fourits an amylin analogue, different receptor family, so treating it as another GLP-1 is the first mistake#cagrilintide · 2025-10-21two_three_liftsamylin not glp-1#cagrilintide · 2025-10-21ruo_onlyCagriSema is cagrilintide with semaglutide and REDEFINE is the trial programme around it, happy to be corrected#cagrilintide · 2025-10-21first_month_fiwhile im here does amylin do something about fullness that the GLP-1 doesnt#cagrilintide · 2025-10-23ghent_gradientamylin is about slowed gastric emptying and satiety signalling, thats the short version and im no pharmacologist#cagrilintide · 2025-10-23appetite_backamylin not glp-1#cagrilintide · 2025-10-24power_cut_piachanged my mind on this, i started thinking amylin was the interesting bit and now i think its the pairing#cagrilintide · 2025-10-24kev_measuresamylin is about slowed gastric emptying and satiety signalling, thats the short version and im no pharmacologist#cagrilintide · 2025-10-27triple_ag_tomchanged my mind on this, i started thinking amylin was the interesting bit and now i think its the pairing#cagrilintide · 2025-10-28no_appetite_niadoes amylin do something about fullness that the GLP-1 doesnt#cagrilintide · 2025-10-28mag_citrateright so amylin analogue, so its not a GLP-1 at all right#cagrilintide · 2025-10-28abdo_two_inchits an amylin analogue, different receptor family, so treating it as another GLP-1 is the first mistake#cagrilintide · 2025-10-30apob_over_ldlsorry to jump in amylin analogue, so its not a GLP-1 at all right#cagrilintide · 2025-11-01reta_resting_hrits an amylin analogue, different receptor family, so treating it as another GLP-1 is the first mistake, happy to be corrected#cagrilintide · 2025-11-01knees_firstchanged my mind on this, i started thinking amylin was the interesting bit and now i think its the pairing#cagrilintide · 2025-11-01knees_firstdoes amylin do something about fullness that the GLP-1 doesnt#cagrilintide · 2025-11-01meniscus_melchanged my mind on this, i started thinking amylin was the interesting bit and now i think its the pairing#cagrilintide · 2025-11-03identity_shiftsomeone explain why cagri plus sema is supposed to be more than the sum#cagrilintide · 2025-11-03LC_MS_Lenathe argument is that amylin and GLP-1 satiety signalling converge but do not overlap completely#cagrilintide · 2025-11-03LC_MS_LenaREDEFINE 1 — cagrilintide-semaglutide 2.4 mg / 2.4 mg in obesity#cagrilintide · 2025-11-03LC_MS_Lenaand importantly it had cagrilintide alone and semaglutide alone as separate arms, so you can actually see the components#cagrilintide · 2025-11-03identity_shiftso the combo is roughly sema plus a bit, not sema plus cagri#cagrilintide · 2025-11-03tokyo_taperCagriSema is cagrilintide with semaglutide and REDEFINE is the trial programme around it#cagrilintide · 2025-11-06fridge_six_twoupdate on the earlier thing amylin is about slowed gastric emptying and satiety signalling, thats the short version and im no…#cagrilintide · 2025-11-06invoice_mismatchamylin is about slowed gastric emptying and satiety signalling, thats the short version and im no pharmacologist#cagrilintide · 2025-11-12glasgow_vialchanged my mind on this, i started thinking amylin was the interesting bit and now i think its the pairing#cagrilintide · 2025-11-12glasgow_vialamylin analogue, so its not a GLP-1 at all right#cagrilintide · 2025-11-12provincial_patamylin not glp-1#cagrilintide · 2025-11-13coa_or_copeamylin analogue, so its not a GLP-1 at all right#cagrilintide · 2025-11-13meniscus_melchanged my mind on this, i started thinking amylin was the interesting bit and now i think its the pairing, n of 1 obviously#cagrilintide · 2025-11-13mg_per_mlCagriSema is cagrilintide with semaglutide and REDEFINE is the trial programme around it#cagrilintide · 2025-11-15sharps_comedyCagriSema is cagrilintide with semaglutide and REDEFINE is the trial programme around it#cagrilintide · 2025-11-16mood_dip_mariits an amylin analogue, different receptor family, so treating it as another GLP-1 is the first mistake#cagrilintide · 2025-11-16non_scale_windoes amylin do something about fullness that the GLP-1 doesnt#cagrilintide · 2025-11-18