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#cagrilintide 2025-12-07

Sunday24 messages7 participantstimes are UTC
Highlights from this day
  • chaser_chris — its an amylin analogue, different receptor family, so treating it as another GLP-1 is the first mistake 03:49
  • retention_time — does amylin do something about fullness that the GLP-1 doesnt its an amylin analogue, different receptor family, so treating it as another GLP-1 is the first mistake 07:08
  • gall_bladder_gav — two VendorInvestigate results on the same GL Biochem lot came back 99.4 and 97.4, closer than i expected 07:57
SS

the fullness effect hasnt faded over 7 months, unlike my semaglutide appetite curve

VV

ok so $185 for a 40 vial and it lasts me longer than the GLP-1 does at my doses

VV

unrelated but is the combination just the two dosed together or a single formulation

SS

the nausea felt different rather than less, more fullness and less of the queasy wave

CC

the numbers everyone quotes come from the combination, so comparing them to monotherapy logs is unfair

CC

its an amylin analogue, different receptor family, so treating it as another GLP-1 is the first mistake

peptidemeter-summary-kp-0925.pdf
2 pages · 591 KB · not retained in the public archive

how slow are people titrating this compared to semaglutide

did anyone add this to an existing retatrutide dose rather than starting both

AA

lost 37lb over 6 months on the combination and i genuinely cannot apportion it

genuine question is anyone running this on its own or is it all CagriSema in here

RT

does amylin do something about fullness that the GLP-1 doesnt
its an amylin analogue, different receptor family, so treating it as another GLP-1 is the first mistake

[edited]
VV

i was sceptical about monotherapy and after 8 months im still sceptical, just less so

monotherapy question, did appetite move for you without a GLP-1 alongside

GB

two VendorInvestigate results on the same GL Biochem lot came back 99.4 and 97.4, closer than i expected