the slower titration in here is community habit as much as anything, the trials had their own schedule, i could be wrong
#cagrilintide 2025-12-27
Saturday20 messages7 participantstimes are UTC
Highlights from this day
- taper_tess — follow up i titrated over twice as many weeks as i did on semaglutide and that was right for me 16:06
- pbs_pip — did the combination change your GI compared to the GLP-1 alone lost 27lb over 15 months on the combination and i genuinely cannot apportion it 16:33
- dexa_or_bia — two Medutest results on the same QSC lot came back 99 and 99.2, closer than i expected 17:07
the fullness thing is the part people describe differently, food stops being interesting rather than repellent, ill dig out the number
is the weekly schedule the same here
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is 2.4 the number for this too or am i confusing compounds
follow up i titrated over twice as many weeks as i did on semaglutide and that was right for me
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did the combination change your GI compared to the GLP-1 alone
lost 27lb over 15 months on the combination and i genuinely cannot apportion it
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£240 for a 5 vial and it lasts me longer than the GLP-1 does at my doses
underwhelming honestly
[edited]while im here did the nausea feel different to you or just less
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update on the earlier thing is the combination just the two dosed together or a single formulation
two Medutest results on the same QSC lot came back 99 and 99.2, closer than i expected
monotherapy was underwhelming for me and i say that as someone who wanted it to work
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slower than the others
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for the archive anyone stopped the GLP-1 and kept only this
the fullness effect hasnt faded over 22 months, unlike my semaglutide appetite curve
separate days
monotherapy here
is there a reason people titrate this over more weeks than the others
whats REDEFINE testing exactly
REDEFINE is the phase 3 programme, most of what gets quoted casually in here is earlier work