5 in 1.5ml gives 5mg/ml which is what i use, purely because the units come out round
the combination is the thing with trial data behind it, monotherapy in here is mostly us guessing
#cagrilintide 2025-12-06
Saturday24 messages5 participantstimes are UTC
Highlights from this day
- blank_run — you cannot tell which of the two is doing what in a combination and i stopped pretending i could 20:27
- declared_value — the nausea felt different rather than less, more fullness and less of the queasy wave 20:38
- declared_value — the fullness thing is the part people describe differently, food stops being interesting rather than repellent 21:21
- declared_value — amylin is about slowed gastric emptying and satiety signalling, thats the short version and im no pharmacologist 21:38
- drawup_dee — for the archive the fullness effect hasnt faded over 1 months, unlike my semaglutide appetite curve 21:42
the reason nausea reads differently is timing, mine arrived on the second day rather than the first
CagriSema is cagrilintide with semaglutide and REDEFINE is the trial programme around it
follow up the numbers everyone quotes come from the combination, so comparing them to monotherapy logs is unfair, i have it written down somewhere
you cannot tell which of the two is doing what in a combination and i stopped pretending i could
🎉8✅15
underwhelming honestly
[edited]is the combination just the two dosed together or a single formulation
the nausea felt different rather than less, more fullness and less of the queasy wave
is the weekly schedule the same here
dosing them on different days made no difference i could detect
thats the phase 3 one
slower than the others
held mine a while
the fullness thing is the part people describe differently, food stops being interesting rather than repellent
📉5✅3⚠️9
is anyone running this on its own or is it all CagriSema in here
amylin is about slowed gastric emptying and satiety signalling, thats the short version and im no pharmacologist
🙏18🤝16
monotherapy did work for me, just slower and smaller than i expected
for the archive the fullness effect hasnt faded over 1 months, unlike my semaglutide appetite curve
janoshik-b-0329.pdf
2 pages · 258 KB · not retained in the public archive
the slower titration in here is community habit as much as anything, the trials had their own schedule
is there a reason people titrate this over more weeks than the others
changed my mind on this, i started thinking amylin was the interesting bit and now i think its the pairing
the combination is the thing with trial data behind it, monotherapy in here is mostly us guessing, someone check my working
monotherapy here
went slower because the first step gave me two rough days and i took that as information