vialroom

#cagrilintide 2026-01-14

Wednesday12 messages3 participantstimes are UTC
Highlights from this day
  • void_volume — did the nausea feel different to you or just less 19:37
  • back_from_away — the slower titration in here is community habit as much as anything, the trials had their own schedule, i think 20:47
  • swirl_not_shake — follow up i titrated over twice as many weeks as i did on semaglutide and that was right for me, happy to be corrected 20:50
  • swirl_not_shake — is there a reason people titrate this over more weeks than the others noticed something around week 25 on monotherapy, well after i had given up expecting to 20:51
VV

monotherapy was underwhelming for me and i say that as someone who wanted it to work

VV

did the nausea feel different to you or just less

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BF

the reason nausea reads differently is timing, mine arrived on the second day rather than the first

[edited]

the slower titration in here is community habit as much as anything, the trials had their own schedule, i think

follow up i titrated over twice as many weeks as i did on semaglutide and that was right for me, happy to be corrected

Cited study
Efficacy and Safety of Cagrilintide in Adults with Overweight or Obesity — Phase 2
The Lancet · 2021
Cagrilintide monotherapy, dose ranging. The combination trials came later.
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is there a reason people titrate this over more weeks than the others
noticed something around week 25 on monotherapy, well after i had given up expecting to

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BF

REDEFINE is the trial

Cited study
Efficacy and Safety of Cagrilintide in Adults with Overweight or Obesity — Phase 2
The Lancet · 2021
Cagrilintide monotherapy, dose ranging. The combination trials came later.