the winter risk is freezing, not cooking

The Canadian channel spent a fortnight explaining a hazard the rest of the room had not considered. A parcel sitting in an unheated depot overnight at minus twenty is a different problem from a parcel in a hot van, and the freeze-thaw conversation that followed was the most technical thing the cold-chain channel had done all year.

• Freezing lyophilised powder is largely uneventful, and freezing reconstituted solution is the case where people report visible change.
• A member in Manitoba described three winters of depot delays and gave the room a rule of thumb about ordering before the first hard freeze.
• Repeated freeze-thaw cycles rather than a single freeze were identified as the thing worth avoiding, based on general protein handling rather than any trial here.
• Provincial coverage was described accurately as thirteen separate answers, and the pinned table got a date stamp so people stop quoting a stale version.
• GGPeps came up for shipping that arrived faster than quoted into Canada twice running, which the channel logged without generalising.