is the GI worse than tirzepatide or about the same
❤️2📉3📈2
#retatrutide 2024-12-01
Sunday45 messages10 participantstimes are UTC
Highlights from this day
- mg_per_ml — i log resting heart rate every morning because of this and its the one number i actually watch 16:02
- amylin_amy — the heart rate thing is real enough that i mention it whenever someone asks about starting 16:34
- warsaw_vial — research use only is on every vial and i treat it as exactly that, nobody here is prescribing 17:03
- split_dose_sam — phase 2 doses are published and theyre not far off what people here run, coincidence rather than plan 19:53
- VialBot — Batch lookup E-2205: 3 independent reports on file, earliest 2024-08-09. 21:28
the half life supports weekly dosing and thats what ive done from the start
settled by month three
glucagon is the new bit
🙏1
low and slow
i log resting heart rate every morning because of this and its the one number i actually watch
🧊1🎉15📈1
the phase 2 weight result was larger than what the earlier agonists reported, in a smaller shorter trial
low and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom
my resting heart rate is up about 3 bpm, did that settle for anyone
phase 2 only
mine went up too
anyone logging resting heart rate on this
smaller steps here
did the phase 2 plateau or was it still moving at the end
🧊4
the heart rate thing is real enough that i mention it whenever someone asks about starting
medutest-report-b-0114.pdf
3 pages · 878 KB · not retained in the public archive
nobody should read my log as a plan, im recording what i did and thats all it is
[edited]right so im at 12 and the appetite effect is stronger than i expected, normal
there is no long term safety data, phase 2 and an ongoing phase 3 programme is what exists
phase 2 doses are published and theyre not far off what people here run, coincidence rather than plan
research use only is on every vial and i treat it as exactly that, nobody here is prescribing
watching my heart rate
anyone stayed at 2.5 for months rather than climbing
GI was about the same as tirzepatide for me, the difference was how fast it arrived
back after 7 months, has anything actually been published since
buying this is a completely different risk conversation from the licensed compounds and that gets said too rarely
follow up blood pressure stayed flat for me while heart rate moved, which i didnt expect
anyone gone above 2.4 and what changed
sorry to jump in whats the half life like, is it weekly the same way
held mine ages
cant feel it honestly
📈18👍11
did the phase 2 result actually come in higher than the tirzepatide numbers
the glucagon arm is the mechanistic story for extra energy expenditure and its still a story to me
no long term data
did anyone come off because of the heart rate
how do people square the research use only framing with logging their own use
is TRIUMPH the phase 3 programme
quick one how slow is low and slow here, four weeks a step or longer
appetite suppression at 7.5 was stronger than my tirzepatide experience at a comparable point
phase 2 doses are published and theyre not far off what people here run, coincidence rather than plan
update on the earlier thing people insist on small steps because the side effects arrive faster than on the other two
came off at 16 weeks because my resting rate stayed elevated and i didnt like it
whats a sensible starting point, im seeing everything from 0.5 to 2
does the glucagon arm explain the heart rate or is that unrelated
the purity spread across lots worries me more than the molecule does
Batch lookup E-2205: 3 independent reports on file, earliest 2024-08-09.
✅3
my resting rate went up 5 bpm in the first month and came back most of the way by month 24