Topic
Counterion content
Page 4 of 10 — TFA versus acetate salt, what it does to the mass balance, and why an honest 10mg vial can weigh 11.4mg of powder.
Messages — page 4 of 10
bea_reconstitutesgross powder mass is not net peptide. water and counterion are in that number, ill dig out the number#reconstitution · 2025-08-12u100_patgross powder mass is not net peptide. water and counterion are in that number#reconstitution · 2025-08-15truncation_trunet peptide is gross mass minus water minus counterion. that is why 11.4mg of powder can be a correct 10mg vial#coa-reading · 2025-08-16karl_fischerwhat does net peptide content mean next to gross mass#coa-reading · 2025-08-16sulphur_burpgross powder mass is not net peptide. water and counterion are in that number, for what its worth#reconstitution · 2025-08-17deamidationthats the counterion#coa-reading · 2025-08-17tga_noticetfa or acetate, how do i tell from the paperwork#coa-reading · 2025-08-17u100_patwhat does net peptide content mean next to gross mass#coa-reading · 2025-08-17lisbon_lotthats the counterion#coa-reading · 2025-08-19lisbon_lotwhat does net peptide content mean next to gross mass#coa-reading · 2025-08-23u100_patgross powder mass is not net peptide. water and counterion are in that number#reconstitution · 2025-08-24LC_MS_Lenawhat does net peptide content mean next to gross mass gross mass on a jewellery scale plus the water content is enough to…#coa-reading · 2025-08-26motivation_gonewhat does net peptide content mean next to gross mass if you only read one line on a certificate, read the lot number. if you…#coa-reading · 2025-08-29vialkeepernet peptide is gross mass minus water minus counterion. that is why 11.4mg of powder can be a correct 10mg vial#coa-reading · 2025-08-30plateau_pentfa or acetate, how do i tell from the paperwork#coa-reading · 2025-09-03plateau_pentfa counterion runs higher by mass than acetate. if the certificate does not say, you cannot do the mass balance#coa-reading · 2025-09-03lot_number_loutfa or acetate, how do i tell from the paperwork#coa-reading · 2025-09-05alcohol_hitsnet peptide is gross mass minus water minus counterion. that is why 11.4mg of powder can be a correct 10mg vial#coa-reading · 2025-09-09u100_patthats the counterion#coa-reading · 2025-09-09tail_factortfa counterion runs higher by mass than acetate. if the certificate does not say, you cannot do the mass balance#coa-reading · 2025-09-09chlorhexgross powder mass is not net peptide. water and counterion are in that number#reconstitution · 2025-09-10peak_splitwhat does net peptide content mean next to gross mass#coa-reading · 2025-09-10assay_not_puritynet peptide is gross mass minus water minus counterion. that is why 11.4mg of powder can be a correct 10mg vial#coa-reading · 2025-09-10assay_not_puritytfa counterion runs higher by mass than acetate. if the certificate does not say, you cannot do the mass balance, i have it…#coa-reading · 2025-09-10apob_over_ldlnet peptide is gross mass minus water minus counterion. that is why 11.4mg of powder can be a correct 10mg vial#coa-reading · 2025-09-12see_a_clinicianthats the counterion#coa-reading · 2025-09-12lisbon_lottfa or acetate, how do i tell from the paperwork#coa-reading · 2025-09-14karl_fischerthats the counterion#coa-reading · 2025-09-14coa_or_copefor the archive tfa counterion runs higher by mass than acetate. if the certificate does not say, you cannot do the mass balance#coa-reading · 2025-09-14shame_and_medsnet peptide is gross mass minus water minus counterion. that is why 11.4mg of powder can be a correct 10mg vial, your mileage…#coa-reading · 2025-09-14HPLC_Hanknet peptide is gross mass minus water minus counterion. that is why 11.4mg of powder can be a correct 10mg vial#coa-reading · 2025-09-20bengaluru_bactfa or acetate, how do i tell from the paperwork#coa-reading · 2025-09-20endotoxin_edtfa counterion runs higher by mass than acetate. if the certificate does not say, you cannot do the mass balance#coa-reading · 2025-09-20monoisotopicthats the counterion#coa-reading · 2025-09-22non_scale_wintfa counterion runs higher by mass than acetate. if the certificate does not say, you cannot do the mass balance#coa-reading · 2025-09-23logrotatetfa counterion runs higher by mass than acetate. if the certificate does not say, you cannot do the mass balance#coa-reading · 2025-09-26logrotatewhat does net peptide content mean next to gross mass#coa-reading · 2025-09-26vialkeepernet peptide is gross mass minus water minus counterion. that is why 11.4mg of powder can be a correct 10mg vial#coa-reading · 2025-09-28ferrous_ashwhat does net peptide content mean next to gross mass#coa-reading · 2025-09-28ferrous_ashtfa counterion runs higher by mass than acetate. if the certificate does not say, you cannot do the mass balance, ymmv#coa-reading · 2025-09-28taper_tessthats the counterion#coa-reading · 2025-09-28underfill_umanet peptide is gross mass minus water minus counterion. that is why 11.4mg of powder can be a correct 10mg vial#coa-reading · 2025-09-30seizure_letternet peptide is gross mass minus water minus counterion. that is why 11.4mg of powder can be a correct 10mg vial#coa-reading · 2025-10-02tarpit_tamgross powder mass is not net peptide. water and counterion are in that number, someone check my working#reconstitution · 2025-10-03chlorhexnet peptide is gross mass minus water minus counterion. that is why 11.4mg of powder can be a correct 10mg vial#coa-reading · 2025-10-03mg_per_mltfa counterion runs higher by mass than acetate. if the certificate does not say, you cannot do the mass balance#coa-reading · 2025-10-03ms_ms_mirathats the counterion#coa-reading · 2025-10-03otto_swirlsnet peptide is gross mass minus water minus counterion. that is why 11.4mg of powder can be a correct 10mg vial#coa-reading · 2025-10-06snac_and_watertfa or acetate, how do i tell from the paperwork#coa-reading · 2025-10-06identity_shiftthats the counterion#coa-reading · 2025-10-06area_percenttfa or acetate, how do i tell from the paperwork#coa-reading · 2025-10-09area_percentwhat does net peptide content mean next to gross mass#coa-reading · 2025-10-09plus_sixteenfollow up tfa counterion runs higher by mass than acetate. if the certificate does not say, you cannot do the mass balance#coa-reading · 2025-10-11noct.titratewhat does net peptide content mean next to gross mass#coa-reading · 2025-10-13cross_border_camfor the archive tfa or acetate, how do i tell from the paperwork mixed fonts and inconsistent kerning in one document is worth…#coa-reading · 2025-10-13blank_runwhat does the COA say for water content and counterion#coa-reading · 2025-10-13cat_on_the_trayKF 5.8%. nothing about counterion#coa-reading · 2025-10-13blank_runthen some of your missing 1.1mg is water and probably a chunk more is acetate or TFA, and the vendor is not necessarily lying#coa-reading · 2025-10-13blank_runnow counterion. peptides come off the purification as a salt. TFA salt if they used TFA in the mobile phase, acetate if they…#coa-reading · 2025-10-13blank_runone way your 8.9 happens with nobody lying to you#coa-reading · 2025-10-13