10 was enough
#tirzepatide 2026-03-05
Thursday37 messages9 participantstimes are UTC
Highlights from this day
- rotate_the_site — the GIP explanation for easier nausea is plausible and i still treat it as a story not a fact 15:47
- gip_glp_gil — held 10 for 14 months and lost 32kg over that stretch, slow and boring and fine, your mileage will differ 17:15
- gip_glp_gil — coming off semaglutide, is there a conversion or do i restart at 2.5 17:35
- coa_or_cope — i log everything and my appetite curve looks flatter across the week than my semaglutide log did, happy to be corrected 17:55
- coa_or_cope — does the appetite effect feel different or just stronger 18:39
restarted at 2.5 after 8 months off and the first two doses reminded me why titration exists, i think
*VendorInvestigate not the other one
coming back to this does the GIP arm actually explain the easier nausea or is that hand waving
went back to semaglutide after 14 months because the cost difference mattered more than the GI
whats the plateau pattern here, same as semaglutide or different
unrelated but the 2.5 to 5 step was the roughest one for me and everything after was easier
40 units of a 5 solution is a lot of volume and i check that one twice every single time
GI was noticeably easier for me than semaglutide at what felt like the same appetite effect
[edited]no clean conversion
changed my mind about needing 15, i was chasing a number rather than an outcome
the GIP explanation for easier nausea is plausible and i still treat it as a story not a fact
🔥10📉8👀4
while im here back after 25 months, do i restart at 2.5 or pick up near where i left off
titrate slow
the 40 vial in 1ml gives 4mg/ml which puts 15 on 50 units, nice round numbers, n of 1 obviously
the two compounds arent interchangeable week for week even if the effect ends up similar
held 10 for 14 months and lost 32kg over that stretch, slow and boring and fine, your mileage will differ
💀11📉12
coming off semaglutide, is there a conversion or do i restart at 2.5
i log everything and my appetite curve looks flatter across the week than my semaglutide log did, happy to be corrected
✅1
switched last year
GIP plus GLP-1
SURMOUNT was the weight programme and SURPASS was diabetes, thats the split people mix up, thats just me
the sweet spot argument is really about effect per side effect, not a magic number, happy to be corrected
$185 for a 30 vial is roughly what ive paid for the last year
anyone got a 4 recon they like for the 30 vials
does the appetite effect feel different or just stronger
🎉5
anyone stopped at 10 and stayed there for months
checked the units twice
❤️1🎉3
if youre coming off semaglutide the honest answer is start low and find out, theres no table, anyway
i went to 15 and came back to 10, more suppression wasnt more useful for me, n of 1 obviously
at 1 my appetite went completely and i dropped back a step, eating nothing isnt a win
i sat at 7.5 for 24 months and never needed more, which is where the folklore comes from
why does everyone talk about 7.5 and not 10
folklore probably
✅14
5 did nothing
switched from 15 semaglutide and started at 2.5, took the slow route, never regretted it
7.5 gang