switched from 2.4 semaglutide and started at 2.5, took the slow route, never regretted it
held 10 for 8 months and lost 33kg over that stretch, slow and boring and fine
#tirzepatide 2026-01-14
Wednesday14 messages4 participantstimes are UTC
Highlights from this day
- abdo_two_inch — switched from 2.4 semaglutide and started at 2.5, took the slow route, never regretted it held 10 for 8 months and lost 33kg over that stretch, slow and boring and fine 08:00
- zed_zeroes_in — i went to 15 and came back to 10, more suppression wasnt more useful for me, still working it out 08:35
- batch_bandit — no gap when i switched, took the last semaglutide dose and started this a week later 09:15
whats the top licensed dose, 15 or does it go higher
went back to semaglutide after 4 months because the cost difference mattered more than the GI
back after 22 months, do i restart at 2.5 or pick up near where i left off
is there a reason to titrate slower than the four week schedule
[edited]how long before the dual thing was noticeable to you
i went to 15 and came back to 10, more suppression wasnt more useful for me, still working it out
12 did nothing extra over 10 for me and that still holds a year later
the sweet spot thing is survivorship, the people it worked for stayed and said so
i sat at 7.5 for 4 months and never needed more, which is where the folklore comes from
no gap when i switched, took the last semaglutide dose and started this a week later
| Trial schedule | What most people here do | |
|---|---|---|
| Step interval | 4 weeks, fixed | 4-12 weeks, on symptoms |
| Holding | protocol deviation | normal and expected |
| Top dose | reached by design | often never reached |
| Coming down | not studied | common at maintenance |
whats the plateau pattern here, same as semaglutide or different
SURMOUNT-OSA was the sleep apnoea trial and it is not a weight headline however its quoted