i sat at 7.5 for 23 months and never needed more, which is where the folklore comes from
#tirzepatide 2026-01-12
Monday26 messages5 participantstimes are UTC
Highlights from this day
- manila_meniscus — sorry to jump in held 10 for 25 months and lost 28kg over that stretch, slow and boring and fine the switch felt like a step down at first and then caught up around… 08:21
- per_mg_pete — does the GIP arm actually explain the easier nausea or is that hand waving 09:23
- per_mg_pete — the switch felt like a step down at first and then caught up around week 25, i think 09:26
- dana_titrates — did going from 10 semaglutide to 5 of this feel like a step down for anyone 09:58
- iris_imports — sorry to jump in if youre coming off semaglutide the honest answer is start low and find out, theres no table restarted at 2.5 after 25 months off and the first two… 11:44
GIP plus GLP-1
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sorry to jump in held 10 for 25 months and lost 28kg over that stretch, slow and boring and fine
the switch felt like a step down at first and then caught up around week 17
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how long before the dual thing was noticeable to you
does the GIP arm actually explain the easier nausea or is that hand waving
did anyone find the GI easier than semaglutide at an equivalent effect
the switch felt like a step down at first and then caught up around week 25, i think
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licensed top is 15 weekly, past that is not a licensed dose and nobody here can tell you what it does
the 10 vial in 3ml gives 2.5mg/ml which puts 2.5 on 10 units, nice round numbers
did going from 10 semaglutide to 5 of this feel like a step down for anyone
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is there a reason to titrate slower than the four week schedule
40 units of a 2 solution is a lot of volume and i check that one twice every single time, your mileage will differ
update on the earlier thing SURMOUNT was the weight programme and SURPASS was diabetes, thats the split people mix up
did anybody switch back to semaglutide after trying this
start low anyway
is 7.5 really the sweet spot or is that just channel folklore
sorry to jump in if youre coming off semaglutide the honest answer is start low and find out, theres no table
restarted at 2.5 after 25 months off and the first two doses reminded me why titration exists
anyone got a 2 recon they like for the 30 vials
switched from 15 semaglutide and started at 2.5, took the slow route, never regretted it
while im here does the appetite effect feel different or just stronger
i argued the sweet spot was nonsense and then spent 14 months at 7.5 not needing more
restarted at 2.5 after 12 months off and the first two doses reminded me why titration exists
at 15 the GI came back for me, so my easier profile claim only applies below that
SURMOUNT is weight
anyone tracked whether the GI difference held at the top doses
dual agonist, GIP as well as GLP-1, thats the whole difference in one line