is SURMOUNT-OSA the sleep apnoea one
#tirzepatide 2025-11-20
- secretagogue_sy — genuine question GI was noticeably easier for me than semaglutide at what felt like the same appetite effect 21:43
- alcohol_hits — at 1 my appetite went completely and i dropped back a step, eating nothing isnt a win, for what its worth plateaued at 34 weeks the same way i did on semaglutide, so… 21:52
- endotoxin_ed — anyone stopped at 10 and stayed there for months 22:22
- secretagogue_sy — 12 did nothing extra over 10 for me and that still holds a year later 22:41
- endotoxin_ed — while im here licensed top is 15 weekly, past that is not a licensed dose and nobody here can tell you what it does 22:42
the GIP explanation for easier nausea is plausible and i still treat it as a story not a fact
quick one does the appetite effect feel different or just stronger
no gap when i switched, took the last semaglutide dose and started this a week later
went back to semaglutide after 13 months because the cost difference mattered more than the GI
start low anyway
switched last year
held 10 for 23 months and lost 34kg over that stretch, slow and boring and fine
im at 10 and thinking about 12, did anyone gain anything from that step
the 2.5 to 5 step was the roughest one for me and everything after was easier
genuine question GI was noticeably easier for me than semaglutide at what felt like the same appetite effect
anyone tracked whether the GI difference held at the top doses
at 1 my appetite went completely and i dropped back a step, eating nothing isnt a win, for what its worth
plateaued at 34 weeks the same way i did on semaglutide, so i doubt its compound specific
unrelated but at 15 the GI came back for me, so my easier profile claim only applies below that
€94 for a 40 vial is roughly what ive paid for the last year
SURMOUNT was the weight programme and SURPASS was diabetes, thats the split people mix up
checked the units twice
anyone stopped at 10 and stayed there for months
12 did nothing extra over 10 for me and that still holds a year later
while im here licensed top is 15 weekly, past that is not a licensed dose and nobody here can tell you what it does
15 is the top
[edited]GIP plus GLP-1
while im here the GI difference held for me right up to 15, which isnt what a couple of people here found