follow up is the sweet spot argument about effect or about side effects
#tirzepatide 2025-11-19
Wednesday17 messages5 participantstimes are UTC
Highlights from this day
- sulphur_burp — the 5 vial in 1ml gives 2mg/ml which puts 0.25 on 25 units, nice round numbers 22:49
- sulphur_burp — for the archive anyone tracked whether the GI difference held at the top doses 23:02
- endotoxin_ed — there is no clean conversion between the two, anyone giving you a ratio is guessing 23:09
- apob_over_ldl — the GIP explanation for easier nausea is plausible and i still treat it as a story not a fact 23:12
at 2 my appetite is gone entirely, did anyone go down rather than up
did going from 2.4 semaglutide to 5 of this feel like a step down for anyone
no clean conversion
the 5 vial in 1ml gives 2mg/ml which puts 0.25 on 25 units, nice round numbers
📈2👀16🧪1
how long before the dual thing was noticeable to you
why does everyone talk about 7.5 and not 10
5 was where i first noticed it properly, 2.5 did almost nothing for me
for the archive anyone tracked whether the GI difference held at the top doses
[edited]👍12💀5🎉10
how did people handle the 2.5 to 5 jump
anyone stopped at 10 and stayed there for months
i argued the sweet spot was nonsense and then spent 1 months at 7.5 not needing more
there is no clean conversion between the two, anyone giving you a ratio is guessing
⚠️6🧊3👍2
whats the plateau pattern here, same as semaglutide or different
the GIP explanation for easier nausea is plausible and i still treat it as a story not a fact
📈15🧊3😂18
GI was noticeably easier for me than semaglutide at what felt like the same appetite effect
at 15 the GI came back for me, so my easier profile claim only applies below that
😂10