update on the earlier thing the GIP explanation for easier nausea is plausible and i still treat it as a story not a fact
#tirzepatide 2025-09-03
Wednesday31 messages7 participantstimes are UTC
Highlights from this day
changed my mind about needing 15, i was chasing a number rather than an outcome
coming back to this licensed top is 15 weekly, past that is not a licensed dose and nobody here can tell you what it does
i sat at 7.5 for 7 months and never needed more, which is where the folklore comes from
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did anyone find the GI easier than semaglutide at an equivalent effect
the sweet spot thing is survivorship, the people it worked for stayed and said so
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is there a reason to titrate slower than the four week schedule
SURMOUNT-OSA was the sleep apnoea trial and it is not a weight headline however its quoted
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held 10 for 23 months and lost 15kg over that stretch, slow and boring and fine
the 30 vial in 1.5ml gives 8mg/ml which puts 5 on 40 units, nice round numbers
wk 1-4 2.5mg
wk 5-8 5.0mg
wk 9-20 7.5mg <- stayed here
wk 21-24 10.0mg (no extra benefit for me)
wk 25+ 7.5mg (came back down)start low anyway
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titrate slow
is the 20 vial the common one or do people use 2
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€55 for a 10 vial is roughly what ive paid for the last year
the GI difference held for me right up to 15, which isnt what a couple of people here found
checked the units twice
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folklore probably
ok so my Medutest result on a GGPeps vial came in at 98.6 which is why i keep buying from them
there is no clean conversion between the two, anyone giving you a ratio is guessing
*Medutest not the other one
i went to 15 and came back to 10, more suppression wasnt more useful for me
anyone got a 8 recon they like for the 10 vials
follow up restarted at 2.5 after 7 months off and the first two doses reminded me why titration exists, anyway
sorry to jump in GI was noticeably easier for me than semaglutide at what felt like the same appetite effect
at 10 my appetite is gone entirely, did anyone go down rather than up
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5 did nothing
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is the sweet spot argument about effect or about side effects
coming off semaglutide, is there a conversion or do i restart at 2.5
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15 is the top
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plateaued at 6 weeks the same way i did on semaglutide, so i doubt its compound specific
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