five week steps worked better for me than four, purely on how the second week felt
#semaglutide 2025-10-10
Friday36 messages10 participantstimes are UTC
Highlights from this day
- vat_on_import — whats the actual licensed ceiling, i keep seeing different numbers 13:03
- food_noise_off — lost about 32kg on the low doses before i even got to 1, which surprised me 14:39
- cat_on_the_tray — is the plateau usually appetite coming back or just the scale stopping 14:55
- VialBot — Batch lookup E-2205: 5 independent reports on file, earliest 2024-12-27. 17:20
- lead_time_lars — held at 0.25 and lost 48lb over 17 months, slower than the trials and fine by me 17:35
*week 6 not week 9
whats the actual licensed ceiling, i keep seeing different numbers
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FLOW was the kidney outcomes trial and it gets quoted in here for things it didnt measure
unrelated but my plateau was the scale stopping while appetite stayed suppressed, which is a different problem
plateaus move
changed my mind on the four week rule, i think it depends entirely on how the current dose feels
sorry to jump in brand vs compounded, is there a difference people can actually feel
same dose day
anyone compared their 2 vial dosing against the pen increments
how long did the first 13kg take for people at the low doses
went to 2.4 and the extra suppression wasnt worth the GI for me, so i came back down
anyone gone from 7.5 straight to 0.25 or is that too big a jump
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SELECT wasnt weight
follow up is 2.4 the top or do people go past it
seven days ish
wk 1-4 0.25mg
wk 5-10 0.50mg (held 2 extra weeks)
wk 11-14 1.00mg
wk 15-26 1.70mg (held, long)
wk 27+ 2.40mg📈3
lost about 32kg on the low doses before i even got to 1, which surprised me
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is the plateau usually appetite coming back or just the scale stopping
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unrelated but if youre comparing brand to compounded, dose accuracy in the vial is the variable, not the molecule
how did people handle the jump from 1 to 1.7
going slow cost me nothing except time and saved me two bad weeks, thats my whole contribution
steady state takes weeks
did the STEP 4 withdrawal arm show what i think it showed
licensed ceiling for weight is 2.4 weekly, anything above that is not a licensed dose
half life is about a week so youre roughly four to five weeks to steady state on any new dose
moving my dose day by a day or two never did anything noticeable for me
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ok so did anyone hold at 15 longer than four weeks before going up
Batch lookup E-2205: 5 independent reports on file, earliest 2024-12-27.
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STEP 1 ran to 68 weeks. thats the one everyone half remembers
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held at 0.25 and lost 48lb over 17 months, slower than the trials and fine by me
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vial units and pen clicks are different systems, mixing the two is how people end up wrong, your mileage will differ
quick one the long half life flattens the trough more than people expect, i never felt a day seven dip
mine faded too
does moving my dose day by two days matter with a seven day half life