dose day is sunday for me only because thats when i remember, not because sunday matters
#semaglutide 2025-10-09
Thursday41 messages10 participantstimes are UTC
Highlights from this day
- VialBot — Assay note: ERP lot B-0329 reported at 99.4% of label content. 13:28
- protein_floor — i was wrong about the ceiling for a year, i thought 3 existed. it doesnt for the weight indication if youre comparing brand to compounded, dose accuracy in the vial… 15:06
- pinch_not_stretch — ok so steady state is the bit people skip, judging a new dose after eight days tells you almost nothing 15:50
- warsaw_vial — does the seven day half life mean the last two days are weaker 19:08
back after 7 months off, do i restart at 0.25 or somewhere higher
does the licensed ceiling for weight differ from the diabetes one
SELECT wasnt weight
what did SELECT actually measure, i see it quoted for everything
Assay note: ERP lot B-0329 reported at 99.4% of label content.
😂4
right so the long half life flattens the trough more than people expect, i never felt a day seven dip
split_dose_samdose day is sunday for me only because thats when i remember, not because sunday matters
the appetite effect faded for me around 23 months and going up fixed it for a while, someone check my working
does moving my dose day by two days matter with a seven day half life
not the same trial
is 2.4 the top or do people go past it
half life is about a week so youre roughly four to five weeks to steady state on any new dose
five week steps worked better for me than four, purely on how the second week felt
held there too
✅12👍5🧪1
seven days ish
did anyone titrate slower than four weeks a step and how did that go
did anybody find a difference between WWB and pharmacy at the same 12
⚠️3
lost about 27kg on the low doses before i even got to 1, which surprised me
did anyone hold at 10 longer than four weeks before going up
i dont think the plateau is a dose problem most of the time, but i cant prove that
my 30 vial in 1.5ml gives 2mg/ml so 2.5 lands on 20 units, thats why i picked that volume
i was wrong about the ceiling for a year, i thought 3 existed. it doesnt for the weight indication
if youre comparing brand to compounded, dose accuracy in the vial is the variable, not the molecule
✅7
is the plateau usually appetite coming back or just the scale stopping
how did people handle the jump from 1 to 1.7
genuine question is there a reason to hold at 1.7 rather than going to 2.4
ok so steady state is the bit people skip, judging a new dose after eight days tells you almost nothing
🎉2💀7
give it four weeks
STEP is several trials, so saying STEP said x is usually wrong without a number after it
2.4 is the ceiling
how many weeks before you noticed anything at 7.5
is the plateau at 27 weeks normal or am i doing something wrong
moving my dose day by a day or two never did anything noticeable for me, i think
mine faded too
i stayed on 1.7 for 20 months and never went to 2.4, appetite was already where i needed it
how long till steady state, ive read the half life is about a week
how long did the first 20kg take for people at the low doses
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SELECT was cardiovascular outcomes in people with overweight and existing disease, not a weight trial
my dose day drifted from friday to sunday, does that reset anything
plateaus move
does the seven day half life mean the last two days are weaker
wk 1-4 0.25mg
wk 5-10 0.50mg (held 2 extra weeks)
wk 11-14 1.00mg
wk 15-26 1.70mg (held, long)
wk 27+ 2.40mg