changed my mind on the four week rule, i think it depends entirely on how the current dose feels
#semaglutide 2025-07-21
Monday35 messages9 participantstimes are UTC
Highlights from this day
- bpc_sceptic — licensed ceiling for weight is 2.4 weekly, anything above that is not a licensed dose 18:51
- bpc_sceptic — did anybody find a difference between FGP and pharmacy at the same 15 19:37
- LC_MS_Lena — for the archive SELECT was cardiovascular outcomes in people with overweight and existing disease, not a weight trial half life is about a week so youre roughly four… 19:55
- cold_chain_cmdr — coming back to this my dose day drifted from friday to sunday, does that reset anything 20:05
- VialBot — Testing queue: 3 submissions open, 55 awaiting dispatch. 20:58
right so held at 12 and lost 32lb over 3 months, slower than the trials and fine by me
i stayed on 1.7 for 12 months and never went to 2.4, appetite was already where i needed it
dose day is sunday for me only because thats when i remember, not because sunday matters
*that should say weekly
licensed ceiling for weight is 2.4 weekly, anything above that is not a licensed dose
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the plateau hit me at 34 weeks and moved again about a month later without a dose change
im at 10 and stuck, did anyone break a plateau without going up
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my plateau was the scale stopping while appetite stayed suppressed, which is a different problem
went 1 to 1.7 too fast and spent two weeks regretting it, dropped back and repeated the step
*VendorInvestigate not the other one
genuine question does the licensed ceiling for weight differ from the diabetes one
five week steps worked better for me than four, purely on how the second week felt
did anybody find a difference between FGP and pharmacy at the same 15
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does the seven day half life mean the last two days are weaker
sorry to jump in back after 11 months off, do i restart at 0.25 or somewhere higher
STEP 4 had the withdrawal arm, thats the one people quote when they talk about stopping
medutest-report-g-0641.pdf
3 pages · 615 KB · not retained in the public archive
for the archive SELECT was cardiovascular outcomes in people with overweight and existing disease, not a weight trial
half life is about a week so youre roughly four to five weeks to steady state on any new dose
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coming back to this my dose day drifted from friday to sunday, does that reset anything
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STEP is several trials, so saying STEP said x is usually wrong without a number after it
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how long till steady state, ive read the half life is about a week
21 months at 2.4 and the honest summary is diminishing returns after the first half
*VendorInvestigate not the other one
held there too
Testing queue: 3 submissions open, 55 awaiting dispatch.
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the trials titrated on a fixed schedule, most people here dont, worth remembering when comparing
does anyone actually run a five week step instead of four
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On this day 9 years ago this channel logged 19 messages.
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anyone gone from 2.4 straight to 7.5 or is that too big a jump
wk 1-4 0.25mg
wk 5-10 0.50mg (held 2 extra weeks)
wk 11-14 1.00mg
wk 15-26 1.70mg (held, long)
wk 27+ 2.40mgif youre comparing brand to compounded, dose accuracy in the vial is the variable, not the molecule
i held at 1 for 6 months and it was the best decision i made
is the plateau usually appetite coming back or just the scale stopping
slower worked better
is there a reason to hold at 1.7 rather than going to 2.4
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SELECT wasnt weight