anyone compared their VendorInvestigate purity across two different SGN lots
#retatrutide 2025-05-28
Wednesday45 messages11 participantstimes are UTC
Highlights from this day
- turnaround_tam — the honest position is this has less human evidence behind it than anything else discussed here, anyway 16:31
- unsolicited_dm — how long before people saw the first change at 10 19:13
- unsolicited_dm — whats a sensible starting point, im seeing everything from 0.5 to 2 19:29
- unsolicited_dm — glucagon is the new bit, ask me again in a month 21:12
does the glucagon arm explain the heart rate or is that unrelated
research use only is on every vial and i treat it as exactly that, nobody here is prescribing
the honest position is this has less human evidence behind it than anything else discussed here, anyway
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i said 4 months ago that my heart rate had settled and it has stayed settled since, i think
settled by month three
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stopped for 11 months and restarted at half my old dose, the ramp was easier second time
my resting heart rate is up about 4 bpm, did that settle for anyone
came off at 34 weeks because my resting rate stayed elevated and i didnt like it, i think
the glucagon arm is the mechanistic story for extra energy expenditure and its still a story to me
nobody should read my log as a plan, im recording what i did and thats all it is, from memory
smaller steps here
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cant feel it honestly
TRIUMPH is phase 3
[redacted at member request] · archive policy
logging rhr daily
[edited]i log resting heart rate every morning because of this and its the one number i actually watch
research use only
sat at 2.5 for 7 months rather than climbing and it kept working, so i never went up
GI was about the same as tirzepatide for me, the difference was how fast it arrived
low and slow
i went up too fast, got a fortnight of nothing but nausea, and dropped back two steps
phase 2 only
glucagon is the new bit
my resting rate went up 9 bpm in the first month and came back most of the way by month 7
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Reminder for unsolicited_dm: dose day is today. Set 8 days ago.
right so the half life supports weekly dosing and thats what ive done from the start
how long before people saw the first change at 10
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whats a sensible starting point, im seeing everything from 0.5 to 2
fridge-temps.csv
125 rows · not retained in the public archive
appetite suppression at 12 was stronger than my tirzepatide experience at a comparable point
there is no long term safety data, phase 2 and an ongoing phase 3 programme is what exists
quick one triple agonist meaning GLP-1, GIP and glucagon, have i got that right
energy expenditure isnt something i could feel, though my sleep tracker disagreed with me
held mine ages
people insist on small steps because the side effects arrive faster than on the other two
ok so back after 14 months, has anything actually been published since
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watching my heart rate
stepping in 2.4 increments instead of doubling is the only thing i would change if i started again
reconstituted the 40 vial to 8mg/ml specifically so i could take 2.4 without measuring crumbs
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reta_resting_hrpeople insist on small steps because the side effects arrive faster than on the other…
why does everyone insist on smaller steps here than on the other two
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no long term data
follow up the purity spread across lots worries me more than the molecule does
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phase 2 doses are published and theyre not far off what people here run, coincidence rather than plan, i could be wrong
triple agonist, GLP-1 and GIP and glucagon. the glucagon arm is the part with no long history, i have it written down somewhere
glucagon is the new bit, ask me again in a month
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