no idea whether the heart rate settles for everyone, mine did and one log isnt data
#retatrutide 2025-05-25
Sunday37 messages10 participantstimes are UTC
Highlights from this day
- deamidation — how do people square the research use only framing with logging their own use 15:07
- tokyo_taper — the half life supports weekly dosing and thats what ive done from the start 15:23
- triumph_watch — reconstituted the 20 vial to 10mg/ml specifically so i could take 5 without measuring crumbs 16:18
- vacuum_vic — phase 2 was still trending at the end which is why the phase 3 readout matters more than usual 16:30
- leeds_ledger — there is no long term safety data, phase 2 and an ongoing phase 3 programme is what exists, ask me again in a month 16:33
mine went up too
held at 0.25 for 3 months and it never plateaued for me, which i cant explain
watching my heart rate
for the archive low and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom
smaller steps here
appetite suppression at 10 was stronger than my tirzepatide experience at a comparable point
research use only
logging rhr daily
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coming back to this why does everyone insist on smaller steps here than on the other two
nobody should read my log as a plan, im recording what i did and thats all it is
how do people square the research use only framing with logging their own use
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blood pressure stayed flat for me while heart rate moved, which i didnt expect
low and slow
the half life supports weekly dosing and thats what ive done from the start
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the purity spread across lots worries me more than the molecule does
anyone compared their Janoshik purity across two different MKM lots
stepping in 12 increments instead of doubling is the only thing i would change if i started again
reconstituted the 20 vial to 10mg/ml specifically so i could take 5 without measuring crumbs
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how long before people saw the first change at 10
🔥5
phase 2 was still trending at the end which is why the phase 3 readout matters more than usual
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lost 14kg over 9 months at doses well under what the trials used, not advice obviously
there is no long term safety data, phase 2 and an ongoing phase 3 programme is what exists, ask me again in a month
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TRIUMPH is the phase 3 programme, thats the name to search rather than the molecule
settled by month three
did anyone come off because of the heart rate
research use only is on every vial and i treat it as exactly that, nobody here is prescribing
unrelated but buying this is a completely different risk conversation from the licensed compounds and that gets said too rarely, someone check my working
energy expenditure isnt something i could feel, though my sleep tracker disagreed with me, thats one data point
TRIUMPH is phase 3
phase 2 only
anyone stayed at 5 for months rather than climbing
triple agonist yeah
the heart rate thing is real enough that i mention it whenever someone asks about starting
how slow is low and slow here, four weeks a step or longer
came off at 13 weeks because my resting rate stayed elevated and i didnt like it