#retatrutide 2025-01-05

GI was about the same as tirzepatide for me, the difference was how fast it arrived

i said 6 months ago that my heart rate had settled and it has stayed settled since

how slow is low and slow here, four weeks a step or longer

triple agonist meaning GLP-1, GIP and glucagon, have i got that right

stopped for 26 months and restarted at half my old dose, the ramp was easier second time

phase 2 was still trending at the end which is why the phase 3 readout matters more than usual

logging rhr daily

the phase 2 weight result was larger than what the earlier agonists reported, in a smaller shorter trial

for the archive sat at 2.5 for 4 months rather than climbing and it kept working, so i never went up

Inter-lab diff for lot SG-1177: 96.8% vs 99.2%. Within expected range.

research use only

Assay note: SGN lot A-2418 reported at 98.6% of label content.

reconstituted the 2 vial to 2mg/ml specifically so i could take 2.5 without measuring crumbs

the glucagon arm is the mechanistic story for extra energy expenditure and its still a story to me
came off at 9 weeks because my resting rate stayed elevated and i didnt like it

right so stepping in 7.5 increments instead of doubling is the only thing i would change if i started again