Batch lookup D-0718: 5 independent reports on file, earliest 2024-06-25.
#retatrutide 2025-01-04
Saturday47 messages13 participantstimes are UTC
Highlights from this day
- taper_tess — my resting heart rate is up about 4 bpm, did that settle for anyone 18:54
- taper_tess — phase 2 was still trending at the end which is why the phase 3 readout matters more than usual 20:36
- cat_on_the_tray — lost 20kg over 15 months at doses well under what the trials used 22:01
- lyophile_liv — held at 2 for 7 months and it never plateaued for me, which i cant explain 22:47
smaller steps here
came off at 5 weeks because my resting rate stayed elevated and i didnt like it
appetite suppression at 1 was stronger than my tirzepatide experience at a comparable point
quick one did the phase 2 result actually come in higher than the tirzepatide numbers
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no long term data
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the heart rate thing is real enough that i mention it whenever someone asks about starting
low and slow
my resting heart rate is up about 4 bpm, did that settle for anyone
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did the phase 2 plateau or was it still moving at the end
baseline 58
wk 2 61
wk 4 64
wk 6 67
wk 8 66
wk 10 65 (held dose from wk 7)research use only
anyone reconstituting 2 vials to 2 so the steps come out smaller
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anyone stayed at 1.7 for months rather than climbing
cant feel it honestly
held mine ages
triple agonist, GLP-1 and GIP and glucagon. the glucagon arm is the part with no long history
TRIUMPH is phase 3
phase 2 only
coming back to this reconstituted the 15 vial to 5mg/ml specifically so i could take 2.4 without measuring crumbs
VendorInvestigate came back 98.6 on one lot and 96.8 on the next from the same HJ, both fine
people insist on small steps because the side effects arrive faster than on the other two, not advice obviously
GI was about the same as tirzepatide for me, the difference was how fast it arrived
private_script_pripeople insist on small steps because the side effects arrive faster than on the other…
research use only is on every vial and i treat it as exactly that, nobody here is prescribing, still working it out
i said 7 months ago that my heart rate had settled and it has stayed settled since, happy to be corrected
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is TRIUMPH the phase 3 programme
my resting rate went up 5 bpm in the first month and came back most of the way by month 19
phase 2 was still trending at the end which is why the phase 3 readout matters more than usual
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triple agonist yeah
whats a sensible starting point, im seeing everything from 0.5 to 2
settled by month three
[edited]the honest position is this has less human evidence behind it than anything else discussed here
whats the half life like, is it weekly the same way
glucagon is the new bit
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does the energy expenditure claim show up as anything you can feel
i went up too fast, got a fortnight of nothing but nausea, and dropped back two steps, i could be wrong
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no idea whether the heart rate settles for everyone, mine did and one log isnt data
the half life supports weekly dosing and thats what ive done from the start
TRIUMPH is the phase 3 programme, thats the name to search rather than the molecule
lost 20kg over 15 months at doses well under what the trials used
baseline 58
wk 2 61
wk 4 64
wk 6 67
wk 8 66
wk 10 65 (held dose from wk 7)triple agonist meaning GLP-1, GIP and glucagon, have i got that right
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i was wrong to call the heart rate a non issue last year, enough people logged it that i changed my mind
anyone gone above 1.7 and what changed
mine went up too
fridge-thermometer.png
800 × 800 · 115 KB · not retained in the public archive
watching my heart rate
im at 0.25 and the appetite effect is stronger than i expected, normal
held at 2 for 7 months and it never plateaued for me, which i cant explain
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while im here is there any long term safety data at all or is it phase 2 and hope