SNAC does the work
#oral-glp1 2025-09-07
Sunday33 messages6 participantstimes are UTC
Highlights from this day
- apnoea_down_two — absorption is the variable, not the molecule. same tablet, different morning, different result 16:50
- apnoea_down_two — the fasting window is the difference between a dose and a very expensive tablet 17:12
- apnoea_down_two — orforglipron is a small molecule rather than a peptide, which is why the fasting conditions differ, take that with a pinch of salt 17:16
does the 30 minutes start from swallowing or from the water
i do 6am with water and eat at 7, thats been my routine for 19 months
mine was patchy too
ruined my breakfast
🙏13
OASIS ran under the same sort of fasting conditions, thats not the variable between the two
On this day 7 years ago this channel logged 126 messages.
i take mine at 6am, is 30 minutes really enough
right so my oral results were inconsistent week to week and i eventually decided it was me, not the tablet
unrelated but plain water only, about half a glass, then nothing for 30 minutes. i follow it exactly
oral was easier on my gut than injecting at what felt like a similar effect, which surprised me
not a peptide
🎉7🧊18
fasted every morning
set a timer
i said 9 months ago that my oral results were random, they got consistent once i fixed the water
the inconsistency is mostly technique and admitting that took me about a year, i have it written down somewhere
PIONEER not OASIS
about one percent
big mg small dose
⚠️14
for the archive is the inconsistency people report about the drug or about how they take it
*Medutest not the other one
coming back to this splitting a dose made the absorption problem worse rather than better in my own log
i was wrong about the water amount, i was using a sip and it needs a lot more than that
*PeptideMeter not the other one
the 30 minutes starts when you swallow it, and i set a timer because i cannot be trusted
follow up nobody should copy my morning routine, but the timer is the bit i would keep
absorption is the variable, not the molecule. same tablet, different morning, different result
😂16🙏14👀3
ok so is the plain water rule actually load bearing or is it a formality
for the archive my weekly log on oral is noisier than my injectable log ever was, same scales same mornings
the fasting window is the difference between a dose and a very expensive tablet
⚠️17🎉15👀7
why is the oral dose in mg so much bigger than the injectable one
orforglipron is a small molecule rather than a peptide, which is why the fasting conditions differ, take that with a pinch of salt
📈2💀17