no trial for that
#dosing-titration 2026-05-21
Thursday29 messages8 participantstimes are UTC
Highlights from this day
- gip_glp_gil — if you are going up because the scale stalled for two weeks, wait. two weeks is noise 21:19
- VialBot — Recon calculator: 20mg in 3ml = 8mg/ml. 21:42
- travel_cooler — coming back to this the ladder in the trials is a starting point, not a schedule you owe anyone, ask me again in a month 22:19
- customs_owl — the argument for splitting is a flatter curve. the argument against is you have doubled your injections for a guess 22:25
- travel_cooler — if i took it 4 days late do i shift the schedule or go back to the old day 22:50
how do you tell a plateau from just being at your set point
hold
thats anecdote
do you count from injection day or from when you actually felt it
pick a day and stick to it
stepping back down on purpose is a completely reasonable move and this channel should say so more often
if you are going up because the scale stalled for two weeks, wait. two weeks is noise
🧪4
go slower
slightly off topic but appetite returning at the end of the week is extremely common and is not the dose failing
anyone here split their weekly into two and would they do it again
Recon calculator: 20mg in 3ml = 8mg/ml.
👍16🧪18
does a missed week reset anything or do you just carry on
how long did you hold at 7.5 before you moved up
has anyone gone up and then straight back down and been glad they tried
whats a sensible maintenance dose after a year at treatment dose
the trials escalated on a fixed schedule because a trial has to. you are not a trial
n of 1
i would hold
if you are asking whether to go up, the fact you are asking usually means not yet
coming back to this the ladder in the trials is a starting point, not a schedule you owe anyone, ask me again in a month
the argument for splitting is a flatter curve. the argument against is you have doubled your injections for a guess
not advice
you do not have to escalate at all. that is a real option that gets forgotten
whats the smallest step anyone has managed between doses
genuine question is it normal for appetite to come back at the end of the week
the people who do best here are almost always the ones going slowest, i have it written down somewhere
if i took it 4 days late do i shift the schedule or go back to the old day
| Trial schedule | What most people here do | |
|---|---|---|
| Step interval | 4 weeks, fixed | 4-12 weeks, on symptoms |
| Holding | protocol deviation | normal and expected |
| Top dose | reached by design | often never reached |
| Coming down | not studied | common at maintenance |
coming down from 2.4 to 1, how bad is the appetite rebound