with a roughly seven day half-life you are near steady state after about five weeks at a dose
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#dosing-titration 2025-10-31
Friday13 messages5 participantstimes are UTC
Highlights from this day
- nausea_window — with a roughly seven day half-life you are near steady state after about five weeks at a dose 17:48
- VialBot — New independent result logged — KP, lot C-4402, purity 96.8% (Medutest). 17:50
- panel_before_after — the people who do best here are almost always the ones going slowest 18:22
- panel_before_after — appetite returning at the end of the week is extremely common and is not the dose failing 21:48
New independent result logged — KP, lot C-4402, purity 96.8% (Medutest).
what does the room think about jumping a rung to catch up
whats your rule for when a side effect means hold rather than push
came down from a treatment dose to maintenance over about three months and it was uneventful
after a gap of more than about three weeks i restart one rung lower. thats my own rule, not advice
follow up the honest answer is that most of us are running protocols nobody has ever studied
dose day drift is mostly harmless with a weekly compound, but pick a day and defend it
quick one update from 17 months ago: held at the same dose the whole time and still losing slowly
the argument for splitting is a flatter curve. the argument against is you have doubled your injections for a guess
the people who do best here are almost always the ones going slowest
📈16🎉5
came down, no regrets
Reminder for panel_before_after: dose day is today. Set 9 days ago.
appetite returning at the end of the week is extremely common and is not the dose failing
wk 1-4 2.5mg
wk 5-8 5.0mg
wk 9-20 7.5mg <- stayed here
wk 21-24 10.0mg (no extra benefit for me)
wk 25+ 7.5mg (came back down)i hold for two months minimum before i decide a dose has stopped doing anything