vialroom

#dosing-titration 2025-10-30

Thursday15 messages3 participantstimes are UTC
Highlights from this day
  • two_ml_two — the argument for splitting is a flatter curve. the argument against is you have doubled your injections for a guess 17:40
  • two_ml_two — plateau versus set point is not answerable in under six months of data 18:11
  • rotate_the_site — the ladder in the trials is a starting point, not a schedule you owe anyone, your mileage will differ my titration ladder took 22 months to climb and i would do it… 19:28
TM

the argument for splitting is a flatter curve. the argument against is you have doubled your injections for a guess

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TM

i escalate on symptoms. if the current dose is still doing something i stay on it

n of 1

plateau versus set point is not answerable in under six months of data

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FV

appetite returning at the end of the week is extremely common and is not the dose failing

TM

ok so my dose day has drifted 9 days later over 24 months, does it matter

FV

i jumped a rung once to catch up after a supply gap and it was a bad week. would not repeat
i went to the top of the ladder, felt no better than two rungs down, and came back. that is data for me and nobody else

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end of week thing

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if the current dose is still working, going up is spending headroom you might want later

TM

whats the longest anyone has stayed on one dose
stepping back down on purpose is a completely reasonable move and this channel should say so more often