quick one if i hold at 12 indefinitely am i losing anything
#dosing-titration 2024-10-31
Thursday34 messages8 participantstimes are UTC
Highlights from this day
- hr_log_hattie — appetite returning at the end of the week is extremely common and is not the dose failing, take that with a pinch of salt 19:15
- hr_log_hattie — i log dose, day, weight and one line about how the week felt. thats enough to make decisions on 19:24
- revoked_ro — i went from 1.7 to 2.5 and honestly could not tell the difference in appetite i drifted from sunday to wednesday over a year and only noticed when i checked the log 21:23
- low_and_slow — whats the smallest step anyone has managed between doses 21:25
- low_and_slow — stepping back down on purpose is a completely reasonable move and this channel should say so more often 22:10
the argument for splitting is a flatter curve. the argument against is you have doubled your injections for a guess
how long did you hold at 12 before you moved up
a missed week does not reset you, but going straight back to the top dose after a gap is how people get floored
appetite returning at the end of the week is extremely common and is not the dose failing, take that with a pinch of salt
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too early imo
i log dose, day, weight and one line about how the week felt. thats enough to make decisions on
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i hold for two months minimum before i decide a dose has stopped doing anything
plateau versus set point is not answerable in under six months of data
pick a day and stick to it
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dose day drift is mostly harmless with a weekly compound, but pick a day and defend it
with a roughly seven day half-life you are near steady state after about five weeks at a dose
held for months
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split dosing has no trial behind it. people here do it and report on it, thats all
hold
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is there a trial anywhere that studied twice weekly, or is it all anecdote
small steps are better than big ones and the only reason people take big ones is impatience, still working it out
no trial for that
[edited]came down, no regrets
plateau versus set point is not answerable in under six months of data
anyone tracked whether a smaller more frequent dose changed their side effects
quick one holding is not failing. most people here who lasted two years held at least one dose for months
while im here if it "stopped working after four days" that is almost never pharmacokinetics
thats noise
the people who do best here are almost always the ones going slowest, anyway
i have been at 2.4 for 4 months and honestly i have stopped wanting to move
i went up too fast and im paying for it, do i drop back or ride it out
i went from 1.7 to 2.5 and honestly could not tell the difference in appetite
i drifted from sunday to wednesday over a year and only noticed when i checked the log
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whats the smallest step anyone has managed between doses
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what does the room think about jumping a rung to catch up
came down from a treatment dose to maintenance over about three months and it was uneventful
i escalate on symptoms. if the current dose is still doing something i stay on it
stepping back down on purpose is a completely reasonable move and this channel should say so more often
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the honest answer is that most of us are running protocols nobody has ever studied
nobody here can tell you what dose to be on and the ones who try get corrected, not advice obviously
the trials escalated on a fixed schedule because a trial has to. you are not a trial