#dosing-titration 2024-11-02

hold

i hold for two months minimum before i decide a dose has stopped doing anything

end of week thing

anyone tracked whether a smaller more frequent dose changed their side effects

the ladder in the trials is a starting point, not a schedule you owe anyone, ymmv
you do not have to escalate at all. that is a real option that gets forgotten

Purity check: no report on file for lot B-0114. Nothing logged either way.

came down, no regrets

my rule: if a side effect is still there at day five, i hold. if it clears by day three, i step

half life is a week

how do you tell a plateau from just being at your set point

if it "stopped working after four days" that is almost never pharmacokinetics

go slower

i went from 15 to 1.7 and honestly could not tell the difference in appetite

what does the room think about jumping a rung to catch up

thats normal

is there a trial anywhere that studied twice weekly, or is it all anecdote

pick a day and stick to it

a missed week does not reset you, but going straight back to the top dose after a gap is how people get floored

i went to the top of the ladder, felt no better than two rungs down, and came back. that is data for me and nobody else, thats just me