i jumped a rung once to catch up after a supply gap and it was a bad week. would not repeat, happy to be corrected
#dosing-titration 2024-10-28
Monday35 messages7 participantstimes are UTC
Highlights from this day
- a1c_lag — genuine question if i hold at 12 indefinitely am i losing anything 15:42
- plateau_pen — slightly off topic but stepping back down on purpose is a completely reasonable move and this channel should say so more often 18:28
- no_appetite_nia — whats a sensible maintenance dose after a year at treatment dose 18:56
genuine question if i hold at 12 indefinitely am i losing anything
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what does the room think about jumping a rung to catch up
thats noise
i have been at 0.25 for 7 months and honestly i have stopped wanting to move
slightly off topic but how do you tell a plateau from just being at your set point
[edited]if the current dose is still working, going up is spending headroom you might want later, i have it written down somewhere
update question: did anyone who held for 7 months regret it
not advice
steady state is 5 weeks
after a gap of more than about three weeks i restart one rung lower. thats my own rule, not advice
i went to the top of the ladder, felt no better than two rungs down, and came back. that is data for me and nobody else
came down from a treatment dose to maintenance over about three months and it was uneventful, i think
small steps are better than big ones and the only reason people take big ones is impatience
while im here anyone here split their weekly into two and would they do it again
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fridge-thermometer.png
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plateau versus set point is not answerable in under six months of data, ask me again in a month
i drifted from sunday to wednesday over a year and only noticed when i checked the log
coa-e-2205.pdf
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the trials escalated on a fixed schedule because a trial has to. you are not a trial
i went up too fast and im paying for it, do i drop back or ride it out
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two weeks is nothing
is there a trial anywhere that studied twice weekly, or is it all anecdote
[edited]slightly off topic but stepping back down on purpose is a completely reasonable move and this channel should say so more often
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the people who do best here are almost always the ones going slowest
my titration ladder took 2 months to climb and i would do it slower again
go slower
right so with a roughly seven day half-life you are near steady state after about five weeks at a dose
[edited]if it "stopped working after four days" that is almost never pharmacokinetics
my dose day has drifted 5 days later over 20 months, does it matter
whats a sensible maintenance dose after a year at treatment dose
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i log dose, day, weight and one line about how the week felt. thats enough to make decisions on, still working it out
too early imo
my rule: if a side effect is still there at day five, i hold. if it clears by day three, i step
the ladder in the trials is a starting point, not a schedule you owe anyone