€120 for a 2 vial and it lasts me longer than the GLP-1 does at my doses
#cagrilintide 2025-10-10
Friday26 messages6 participantstimes are UTC
Highlights from this day
- night_pin — slightly off topic but held at 2 for 6 months on monotherapy before i touched it again, someone check my working 07:41
- night_pin — i titrated over twice as many weeks as i did on semaglutide and that was right for me 09:56
- verify_or_dont — noticed something around week 25 on monotherapy, well after i had given up expecting to lost 103lb over 16 months on the combination and i genuinely cannot apportion it 10:53
dropped the GLP-1 and stayed on this alone for 19 months, appetite held but weight barely moved
🎉8
REDEFINE is the trial
the numbers everyone quotes come from the combination, so comparing them to monotherapy logs is unfair
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its an amylin analogue, different receptor family, so treating it as another GLP-1 is the first mistake
i keep the two on separate days so if something goes wrong i have a chance of knowing which
back after 26 months, is monotherapy still a minority thing here
the reason nausea reads differently is timing, mine arrived on the second day rather than the first
monotherapy was underwhelming for me and i say that as someone who wanted it to work
the slower titration in here is community habit as much as anything, the trials had their own schedule
if youre used to GLP-1 titration steps this feels absurdly cautious and i still do it that way
slightly off topic but held at 2 for 6 months on monotherapy before i touched it again, someone check my working
monotherapy here
i said earlier this year that monotherapy did nothing for me, and at a higher dose it did something
i titrated over twice as many weeks as i did on semaglutide and that was right for me
💀6⚠️10
follow up weekly for me, same day every week, no reason beyond habit
fullness rather than nausea
slightly off topic but CagriSema is cagrilintide with semaglutide and REDEFINE is the trial programme around it
i was sceptical about monotherapy and after 19 months im still sceptical, just less so
the nausea felt different rather than less, more fullness and less of the queasy wave
nobody should copy my schedule, im describing it because people asked what a slow ramp looks like
🤝9❤️1
added it to an existing tirzepatide dose rather than starting both, which made attribution possible
noticed something around week 25 on monotherapy, well after i had given up expecting to
lost 103lb over 16 months on the combination and i genuinely cannot apportion it
👀16📈1🙏8
combination for me
cagrisema thats it